NOX-B11-2

synthetic oligonucleotide; ghrelin blocking agent; base sequence in first source

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

1.	Body Weight (Weight, Body) 03/01/2006 - "In a 7-d study, DIO mice infused with NOX-B11-2 (33 mg/kg.d, sc) showed body weight loss, compared with animals receiving control SPM. " 03/01/2006 - "Chronic infusion of NOX-B11-2 (33 mg/kg.d, sc) to DIO mice evoked body weight loss for 13 d and reduced food intake and fat mass relative to control SPM-infused mice. "
2.	Weight Loss (Weight Reduction) 03/01/2006 - "This effect was directly mediated by SPM neutralization of ghrelin because NOX-B11-2 administration to ghrelin-deficient mice resulted in no weight loss. "

1.	Ghrelin