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petrotetrayndiol A

a polyacetylene from the sponge Petrosia sp. with anti-proliferative activity; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Acyclic Hydrocarbons
    - Alkynes: 217
      - Polyynes: 10
        petrotetrayndiol A: 1

Experts

1.	Choi, Hye Joung: 1 article (02/2006)
2.	Choi, Yung Hyun: 1 article (02/2006)
3.	Chung, Hae Young: 1 article (02/2006)
4.	Im, Eunok: 1 article (02/2006)
5.	Jung, Jee Hyung: 1 article (02/2006)
6.	Kim, Nam Deuk: 1 article (02/2006)
7.	Park, Sang Eun: 1 article (02/2006)
8.	Yee, Su-Bog: 1 article (02/2006)

Related Diseases

1.

Melanoma (Melanoma, Malignant)

02/08/2006 - "We investigated the possible mechanisms by which petrotetrayndiol A, a polyacetylene from the sponge Petrosia sp., exerts its anti-proliferative activity in cultured SK-MEL-2 human melanoma cells. "
02/08/2006 - "Petrotetrayndiol A induces cell cycle arrest and apoptosis in SK-MEL-2 human melanoma cells through cytochrome c-mediated activation of caspases."

Related Drugs and Biologics

1.	Cytochromes c (Cytochrome c)
2.	Caspases