|1.||Kondo, Nobuhiko: 1 article (02/2006)|
|2.||Oku, Hisae: 1 article (02/2006)|
|3.||Ohizumi, Yasushi: 1 article (02/2006)|
|4.||Nakatani, Keigo: 1 article (02/2006)|
|5.||Ishiguro, Kyoko: 1 article (02/2006)|
|6.||Yamakuni, Tohru: 1 article (02/2006)|
|7.||Aoki, Koichi: 1 article (02/2006)|
02/20/2006 - "Garcinone B reduces prostaglandin E2 release and NF-kappaB-mediated transcription in C6 rat glioma cells."
02/20/2006 - "In the course of our survey of natural compounds inhibiting prostaglandin E2 release and/or lipopolysaccharide (LPS)-induced transcriptional stimulation via NF-kappaB, a central regulator of inflammatory genes, from natural resources, we found garcinone B, a xanthone from callus tissue culture of Hypericum patulum, as a compound with such pharmacological activities, that is a derivative of gamma-mangostin which potently inhibits COX-1 and COX-2 activities to reduce PGE2 release from C6 rat glioma cells, and inhibits IKK activity to prevent NF-kappaB-dependent COX-2 gene transcription. "
|1.||NF-kappa B (NF-kB)