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HO 3089

structure in first source

Also Known As:

HO-3089; HO3089

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzimidazoles: 245
      - HO 3089: 1

Experts

1.	Bellyei, Szabolcs: 1 article (12/2014)
2.	Boronkai, Arpad: 1 article (12/2014)
3.	Cseh, Anna: 1 article (12/2014)
4.	Hideg, Kalman: 1 article (12/2014)
5.	Hocsak, Eniko: 1 article (12/2014)
6.	Kalai, Tamas: 1 article (12/2014)
7.	Pozsgai, Eva: 1 article (12/2014)
8.	Sumegi, Balazs: 1 article (12/2014)
9.	Szabo, Aliz: 1 article (12/2014)

Related Diseases

1.	Neoplasms (Cancer) 12/01/2014 - "HO3089 sensitizes cancer cells to photon irradiation via proapoptotic processes where p53 plays a crucial role. "
2.	Lung Neoplasms (Lung Cancer) 12/01/2014 - "In human U251 glioblastoma and A549 lung cancer cell lines, Erk1/2 and JNK/SAPK were found to mediate this effect of HO3089 since inhibitors of these kinases ameliorated it. "
3.	Glioblastoma (Glioblastoma Multiforme) 12/01/2014 - "In human U251 glioblastoma and A549 lung cancer cell lines, Erk1/2 and JNK/SAPK were found to mediate this effect of HO3089 since inhibitors of these kinases ameliorated it. "
4.	Breast Neoplasms (Breast Cancer) 12/01/2014 - "In murine 4T1 breast cancer cell line, p38 MAPK rather than Erk1/2 or JNK/SAPK was identified as the main mediator of HO3089's radiosensitizing effect. "

Related Drugs and Biologics

1.	p38 Mitogen-Activated Protein Kinases
2.	Radiation-Sensitizing Agents
3.	Phosphotransferases (Kinase)