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SM360320

Proc Natl Acad Sci U S A 2006 Feb 7;103(6):1828-33

Also Known As:

1V136; 9-benzyl-8-hydroxy-2-(2-methoxyethoxy)adenine

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Adenine: 2120
        SM360320: 2

Experts

1.	Aurisicchio, L: 1 article (05/2009)
2.	Ciliberto, G: 1 article (05/2009)
3.	Dharmapuri, S: 1 article (05/2009)
4.	La Monica, N: 1 article (05/2009)
5.	Neuner, P: 1 article (05/2009)
6.	Verdirame, M: 1 article (05/2009)
7.	Carson, Dennis A: 1 article (02/2009)
8.	Chan, Michael: 1 article (02/2009)
9.	Corr, Maripat: 1 article (02/2009)
10.	Datta, Sandip K: 1 article (02/2009)

Related Diseases

1.	Autoimmune Diseases (Autoimmune Disease) 02/24/2009 - "Here, we used a synthetic TLR7 agonist, 9-benzyl-8-hydroxy-2-(2-methoxyethoxy) adenine (SM360320, 1V136) to study TLR7 induced attenuation of inflammatory responses and its application to autoimmune diseases. "
2.	Neoplasms (Cancer) 05/01/2009 - "Additionally, combination of SM360320 with plasmid encoding the extracellular and transmembrane domain of ratHER2/neu affected the spontaneous tumor progression in BALB-neuT mice treated in an advanced disease setting. "
3.	Colonic Neoplasms (Colon Cancer) 05/01/2009 - "These data demonstrate that SM360320 exerts significant antitumor effects and can act in association with DNA-EP for CEA-positive colon cancer and HER2-positive mammary carcinoma. "
4.	Carcinoma (Carcinomatosis) 05/01/2009 - "These data demonstrate that SM360320 exerts significant antitumor effects and can act in association with DNA-EP for CEA-positive colon cancer and HER2-positive mammary carcinoma. "

Related Drugs and Biologics

1.	SM360320
2.	Adenine
3.	DNA (Deoxyribonucleic Acid)