Interleukin-12

A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS.

Also Known As:

IL 12; Interleukin 12; IL12; Interleukin-12 p70; Cytotoxic Lymphocyte Maturation Factor; IL-12 p70; Interleukin 12 p70; Edodekin Alfa; IL-12; Natural Killer Cell Stimulatory Factor

Pharmalogical Action Categories:

Adjuvants, Immunologic
Angiogenesis Inhibitors

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Interleukins: 25257
        Interleukin-12: 9226
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Interleukins: 25257
        Interleukin-12: 9226
Biological Factors: 2472
- Intercellular Signaling Peptides and Proteins: 29768
  - Cytokines: 164289
    - Interleukins: 25257
      - Interleukin-12: 9226

rat Il12a protein

Bio-Agent Context: Research Results