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continuous erythropoietin receptor activator

a third-generation erythropoietic beta molecule created by integrating a large polymer chain into the molecule, thus increasing the molecular weight to twice that of epoetin at approximately 60 kDa; the methoxy-polyethylene glycol polymer chain is integrated via amide bonds between the N-terminal amino group or the e-amino group of lysine (predominantly lysine-52 or lysine-45), using a single succinimidyl butanoic acid linker; an erythropoiesis-stimulating agent for the treatment of anemia
Also Known As:
CERA (erythropoietin receptor activator); Mircera
Networked: 56 relevant articles (3 outcomes, 17 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Beyer, Ulrich: 6 articles (04/2010 - 04/2007)
2. Dougherty, Frank C: 6 articles (04/2010 - 11/2006)
3. Locatelli, Francesco: 5 articles (11/2013 - 07/2007)
4. Cases, Aleix: 4 articles (01/2015 - 05/2007)
5. Villa, Giuseppe: 4 articles (11/2013 - 01/2008)
6. Reigner, Bruno: 4 articles (01/2012 - 11/2006)
7. Endo, Koichi: 3 articles (12/2015 - 01/2012)
8. Tashiro, Yoshihito: 3 articles (12/2015 - 01/2012)
9. Hirata, Michinori: 3 articles (12/2015 - 01/2012)
10. Aizawa, Ken: 3 articles (12/2015 - 01/2012)

Related Diseases

1. Anemia
2. Kidney Diseases (Kidney Disease)
3. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
4. Pain (Aches)
5. Nephrotic Syndrome (Syndrome, Nephrotic)

Related Drugs and Biologics

1. darbepoetin alfa (Aranesp)
2. epoetin beta
3. Polyethylene Glycols (Polyethylene Glycol)
4. Hemoglobins (Hemoglobin)
5. Hematinics
6. Puromycin Aminonucleoside
7. Epoetin Alfa (Epogen)
8. Procollagen-Proline Dioxygenase (Prolyl Hydroxylase)
9. Iron
10. Erythropoietin

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Transplantation (Transplant Recipients)
3. Intravenous Injections
4. Combination Drug Therapy (Combination Chemotherapy)
5. Transplants (Transplant)