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3-O-methylsphingomyelin

Also Known As:

3-O-MeSM

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Experts

1.	Balosso, Silvia: 1 article (12/2008)
2.	Bartfai, Tamas: 1 article (12/2008)
3.	Frasca, Angelisa: 1 article (12/2008)
4.	Maroso, Mattia: 1 article (12/2008)
5.	Ravizza, Teresa: 1 article (12/2008)
6.	Sanchez-Alavez, Manuel: 1 article (12/2008)
7.	Vezzani, Annamaria: 1 article (12/2008)
8.	Caruso, Joseph A: 1 article (12/2005)
9.	Mathieu, Patricia A: 1 article (12/2005)
10.	Reiners, John J: 1 article (12/2005)

Related Diseases

1.	Necrosis 12/01/2005 - "Pre-treatment of 1c1c7 cultures with 3-O-MeSM also suppressed the induction of apoptosis by TNFalpha (tumour necrosis factor alpha), but offered no protection against HA14-1 [ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate], staurosporine, tunicamycin or thapsigargin. "
2.	Seizures (Absence Seizure) 12/01/2008 - "We show here that EEG seizures induced by intrahippocampal injection of kainic acid in C57BL6 adult mice were increased by 2-fold on average by pre-exposure to IL-1beta and this effect was blocked by 3-O-methylsphingomyelin (3-O-MS), a selective inhibitor of the ceramide-producing enzyme sphingomyelinase. "

Related Drugs and Biologics

1.	Staurosporine
2.	Thapsigargin
3.	Tunicamycin
4.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
5.	Benzopyrans
6.	ethyl 2- amino- 6- bromo- 4- (1- cyano- 2- ethoxy- 2- oxoethyl)- 4H- chromene- 3- carboxylate
7.	Sphingomyelin Phosphodiesterase (Sphingomyelinase)
8.	Kainic Acid (Kainate)
9.	Enzymes
10.	Ceramides