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aurasperone A

isolated from Aspergillus aculeatus; structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        aurasperone A: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        aurasperone A: 2

Experts

1.	Abdelaziz, Tarek A: 1 article (01/2021)
2.	Abdelwahab, Ghada Mahmoud: 1 article (01/2021)
3.	Cheng, Yuan-Bin: 1 article (01/2021)
4.	Khalil, Ashraf Taha: 1 article (01/2021)
5.	Lahloub, Mohamed Farid I: 1 article (01/2021)
6.	Mira, Amira: 1 article (01/2021)
7.	Li, H: 1 article (12/2004)
8.	Shan, C Y: 1 article (12/2004)
9.	Song, Y C: 1 article (12/2004)
10.	Tan, R X: 1 article (12/2004)

Related Diseases

1.	Colonic Neoplasms (Colon Cancer) 12/01/2004 - "The present recognition of rubrofusarin B and aurasperone A as strong co-inhibitors on XO, colon cancer cell and some microbial pathogens is of significance for the imperative discovery of new relevant therapeutic agents." 12/01/2004 - "Rubrofusarin B was shown to be cytotoxic to the colon cancer cell line SW1116 (IC50: 4.5 microgml-1), and aurasperone A inhibitory on XO (xanthine oxidase) (IC50: 10.9 micromoll-1). "
2.	Alzheimer Disease (Alzheimer's Disease) 01/01/2021 - "For the first time, some isolated naphtho-γ-pyrones from marine-derived Aspergillus niger, flavasperone (1), rubrofusarin B (2), aurasperone A (3), fonsecinone A (4) in addition to one alkaloid aspernigrin A (7) were invistigated for their inhibitory activity of acetylcholine esterase AChE, a hallmark of Alzheimer's disease (AD). "

Related Drugs and Biologics

1.	rubrofusarin
2.	Xanthine Oxidase
3.	Pyrones
4.	Esterases
5.	Alkaloids
6.	Acetylcholine (Acetylcholine Chloride)
7.	flavasperone
8.	fonsecinone A
9.	aspernigrin A
10.	2,5-dichloro-4-bromophenol (B 2)