8H9 monoclonal antibody

a murine IgG(1) monoclonal antibody that recognizes cell surface tumor antigen broadly distributed on neuroectodermal, epithelial, and mesenchymal tumors, including rhabdomyosarcoma; may have a potential clinical role in radioimmunotherapy

Also Known As:

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Edgar, Mark A: 3 articles (06/2014 - 12/2008)
2.	Luther, Neal: 3 articles (06/2014 - 12/2008)
3.	Souweidane, Mark M: 3 articles (06/2014 - 12/2008)
4.	Cheung, Nai-Kong V: 3 articles (12/2008 - 02/2004)
5.	Guo, Hong-fen: 2 articles (12/2015 - 02/2004)
6.	Larson, Steven M: 2 articles (12/2015 - 10/2005)
7.	Cheung, Nai-Kong: 2 articles (06/2014 - 04/2010)
8.	Gutin, Philip H: 2 articles (04/2010 - 12/2008)
9.	Pastan, Ira: 2 articles (04/2010 - 02/2004)
10.	Ahmed, Mahiuddin: 1 article (12/2015)

Related Diseases

1.	Neoplasms (Cancer) 12/11/2015 - "Anti-B7-H3 mouse monoclonal antibody 8H9 has been successfully used for radioimmunotherapy for patients with B7-H3(+) tumors. " 05/15/2001 - "Monoclonal antibody 8H9 targets a novel cell surface antigen expressed by a wide spectrum of human solid tumors." 02/15/2004 - "The 8H9 monoclonal antibody (MAb) is highly reactive with a cell surface glycoprotein expressed on human breast cancers, childhood sarcomas, and neuroblastomas but is not reactive with the cell surface of normal human tissues. "
2.	Neuroblastoma 05/15/2001 - "Monoclonal antibody 8H9 is a murine IgG1 hybridoma derived from the fusion of mouse myeloma SP2/0 cells and splenic lymphocytes from BALB/c mice immunized with human neuroblastoma. " 02/15/2004 - "The 8H9 monoclonal antibody (MAb) is highly reactive with a cell surface glycoprotein expressed on human breast cancers, childhood sarcomas, and neuroblastomas but is not reactive with the cell surface of normal human tissues. "
3.	Glioma (Gliomas) 12/01/2008 - "Intraparenchymal and intratumoral interstitial infusion of anti-glioma monoclonal antibody 8H9." 04/01/2010 - "Monoclonal antibody 8H9 is specific for membrane protein B7H3 and is reactive with most human high-grade gliomas. "
4.	Sarcoma (Soft Tissue Sarcoma) 02/15/2004 - "The 8H9 monoclonal antibody (MAb) is highly reactive with a cell surface glycoprotein expressed on human breast cancers, childhood sarcomas, and neuroblastomas but is not reactive with the cell surface of normal human tissues. "
5.	Rhabdomyosarcoma 10/01/2005 - "Radioimmunotargeting of human rhabdomyosarcoma using monoclonal antibody 8H9."

Related Drugs and Biologics

1.	Membrane Proteins (Integral Membrane Proteins)
2.	Membrane Glycoproteins (Membrane Glycoprotein)
3.	Immunoglobulin G (IgG)
4.	Surface Antigens (Surface Antigen)

Related Therapies and Procedures

1.	Radioimmunotherapy