2'-deoxy-2'-fluoro-beta-D-arabinonucleic acid

PS-2'F-ANA-DNA chimeras are efficient gene silencing molecules, and suggest that they could have significant therapeutic potential; structure in first source

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Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Damha, Masad J: 1 article (09/2012)
2.	Deleavey, Glen F: 1 article (09/2012)
3.	Soifer, Harris: 1 article (09/2012)
4.	Souleimanian, Naira: 1 article (09/2012)
5.	Stein, Cy A: 1 article (09/2012)
6.	Tiemann, Katrin: 1 article (09/2012)
7.	Wang, Sijian: 1 article (09/2012)

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 09/18/2012 - "In LNCaP prostate cancer cells, gymnotic silencing of the AR by a 2'F-ANA phosphorothioate gapmer oligo led to downstream silencing of cellular prostate-specific antigen (PSA) expression even in the presence of the androgenic steroid R1881 (metribolone), which stabilizes cytoplasmic levels of the AR. "

Related Drugs and Biologics

1.	Prostate-Specific Antigen (Semenogelase)
2.	Metribolone
3.	Steroids