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dimefluron

antineoplastic agent; structure in first source

Also Known As:

3,9-dimethoxy-5-(2-dimethylaminoethoxy)-7H-benzo(c)fluoren-7-one hydrochloride

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Fluorenes: 7
        dimefluron: 2
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Fluorenes: 7
    - dimefluron: 2

Experts

1.	Nobilis, M: 2 articles (04/2005 - 01/2001)
2.	Císar, P: 1 article (04/2005)
3.	Holcapek, M: 1 article (04/2005)
4.	Klimes, J: 1 article (04/2005)
5.	Kolárová, L: 1 article (04/2005)
6.	Kunes, J: 1 article (04/2005)
7.	Pour, M: 1 article (04/2005)
8.	Vybíralová, Z: 1 article (04/2005)
9.	Adamcová, M: 1 article (01/2001)
10.	Gersl, V: 1 article (01/2001)

Related Diseases

1.	Cardiotoxicity 01/01/2001 - "In our study, the cardiotoxicity of repeated i.v. administration (once a week, 10 administrations) of daunorubicin combined with new antineoplastic drugs (with mild side-effects) were followed in two groups of rabbits: 1) Dimefluron (3,9-dimethoxybenfluron hydrochloride-12 mg/kg) + daunorubicin (3 mg/kg), 2) Oracin (6-[2-(2-hydroxyethyl)aminoethyl]-5,11-dioxo-5,6-dihydro-11H- indeno[1,2c]isoquinoline hydrochloride--10 mg/kg) + daunorubicin (3 mg/kg) and compared with the control group (saline--1 ml/kg) and the group with experimentally induced cardiomyopathy (daunorubicin--3 mg/kg). "
2.	Cardiomyopathies (Cardiomyopathy) 01/01/2001 - "In our study, the cardiotoxicity of repeated i.v. administration (once a week, 10 administrations) of daunorubicin combined with new antineoplastic drugs (with mild side-effects) were followed in two groups of rabbits: 1) Dimefluron (3,9-dimethoxybenfluron hydrochloride-12 mg/kg) + daunorubicin (3 mg/kg), 2) Oracin (6-[2-(2-hydroxyethyl)aminoethyl]-5,11-dioxo-5,6-dihydro-11H- indeno[1,2c]isoquinoline hydrochloride--10 mg/kg) + daunorubicin (3 mg/kg) and compared with the control group (saline--1 ml/kg) and the group with experimentally induced cardiomyopathy (daunorubicin--3 mg/kg). "
3.	Body Weight (Weight, Body) 04/29/2005 - "Dimefluron, 3,9-dimethoxy-5-(2-dimethylaminoethoxy)-7H-benzo[c]fluoren-7-one hydrochloride, was administered in a single oral dose (250 mg kg(-1) of body weight) in the form of an aqueous solution via a gastric probe. "

Related Drugs and Biologics

1.	Daunorubicin (Cerubidine)
2.	Antineoplastic Agents (Antineoplastics)
3.	oracine
4.	isoquinoline
5.	Solutions