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1-bromo-2,5-bis(4-hydroxystyryl)benzene

a fluorescent dye that binds amyloid fibrils; structure in first source

Also Known As:

(trans,trans)-1-bromo-2,5-bis(4-hydroxystyryl)benzene; K114 compound

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzylidene Compounds: 10
        Styrenes: 6
        1-bromo-2,5-bis(4-hydroxystyryl)benzene: 1

Experts

1.	Bell-Cohen, Ashlee: 1 article (03/2014)
2.	Dumas, Melanie: 1 article (03/2014)
3.	Lahiri, Debomoy K: 1 article (03/2014)
4.	Mann, Dushyant: 1 article (03/2014)
5.	Paule, Merle G: 1 article (03/2014)
6.	Raymick, James: 1 article (03/2014)
7.	Sarkar, Sumit: 1 article (03/2014)
8.	Schmued, Larry C: 1 article (03/2014)
9.	Zhang, Yi-Hong: 1 article (03/2014)

Related Diseases

1.	Amyloid Plaque 03/01/2014 - "The aim of our current study was to test novel ligands/agents with the potential to disrupt or inhibit the aggregation of Aβ peptide, specifically K114, (trans,trans)-1-bromo-2,5-bis(4-hydroxystyryl)benzene, which was initially developed as a potential positron emission tomography (PET) ligand for the in vivo detection of amyloid plaques. "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Ligands