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2- chloro- N- ((S)- phenyl((2S)- piperidin- 2- yl)methyl)- 3- trifluoromethyl benzamide

Also Known As:

SSR504734

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Boulay, Denis: 2 articles (01/2009 - 11/2005)
2.	Griebel, Guy: 2 articles (01/2009 - 11/2005)
3.	Feldon, Joram: 1 article (08/2009)
4.	Singer, Philipp: 1 article (08/2009)
5.	Yee, Benjamin K: 1 article (08/2009)
6.	Arad, Michal: 1 article (01/2009)
7.	Barak, Segev: 1 article (01/2009)
8.	Black, Mark D: 1 article (01/2009)
9.	De Levie, Amaya: 1 article (01/2009)
10.	Pichat, Philippe: 1 article (01/2009)

Related Diseases

1.

Schizophrenia (Dementia Praecox)

11/01/2005 - "In conclusion, SSR504734 is a potent and selective GlyT1 inhibitor, exhibiting activity in schizophrenia, anxiety and depression models. "
08/01/2009 - "According to the glutamatergic hypofunction hypothesis of schizophrenia, SSR504734 may therefore possess antipsychotic potential. "
01/01/2009 - "SSR103800 and SSR504734 are novel glycine transport 1 (GlyT1) inhibitors with therapeutic potential for the treatment of schizophrenia. "
01/01/2006 - "Since glutamate has been shown to play a role in the regulation of the dopaminergic system in dopamine-related disorders, such as schizophrenia, we investigated the possibility that SSR504734 may modify the basolateral amygdala-elicited stimulation of dopamine release in the nucleus accumbens via an augmentation of glutamate receptor-mediated neurotransmission. "

Related Drugs and Biologics

1.	Glutamic Acid (Glutamate)
2.	Glutamate Receptors (Glutamate Receptor)
3.	Antipsychotic Agents (Antipsychotics)
4.	Glycine (Aminoacetic Acid)
5.	Dopamine (Intropin)