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alaglyzin

an antiarrhythmic based on a clathrate complex of allapinine with glycyrrhizic acid; alaglyzin was less toxic than allapinine

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - Pentacyclic Triterpenes: 108
        Glycyrrhizic Acid: 1041
        alaglyzin: 1
    - Diterpenes: 1470
      - Diterpene Alkaloids: 19
        Aconitine: 466
        alaglyzin: 1
Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Diterpene Alkaloids: 19
    - Aconitine: 466
      - alaglyzin: 1

Experts

1.	Bryzgalov, A O: 1 article (07/2005)
2.	Dolgikh, M P: 1 article (07/2005)
3.	Ganenko, Iu A: 1 article (07/2005)
4.	Sorokina, I V: 1 article (07/2005)
5.	Tolstikova, T G: 1 article (07/2005)
6.	Volkova, E B: 1 article (07/2005)
7.	Zhukova, N A: 1 article (07/2005)

Related Diseases

1.

Cardiac Arrhythmias (Arrythmia)

07/01/2005 - "Pretreatment of the experimental animals with alaglyzin in a dose of 0.25 mg/kg prevented from the arrhythmia development in both tests, while a dose of 0.125 mg/kg was effective only in the CaCl2, test."
07/01/2005 - "The activity of alaglyzin, a new drug based on a clathrate complex of allapinine (well-known antiarrhythmic) with glycyrrhizic acid (GA), was studied on the models of arrhythmia induced by itraperitoneal injections of calcium chloride (CaCl2) and adrenaline (epinephrine) in rats. "

Related Drugs and Biologics

1.	Glycyrrhizic Acid (Glycyrrhizin)
2.	Epinephrine (Adrenaline)
3.	Calcium Chloride (Calcium Chloride, Anhydrous)
4.	allapinin

Related Therapies and Procedures

1.	Injections