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PEI-g-PEG-RGD

PEI-polyethylenimine; PEG - polyethylene glycol; RGD - ACDCRGDCFC; structure in first source

Also Known As:

PEI-g-PEG-RGD conjugate

Networked: 3 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Kim, Sung Wan: 2 articles (03/2011 - 09/2006)
2.	Kim, Won Jong: 2 articles (03/2011 - 09/2006)
3.	Kim, Jihoon: 1 article (03/2011)
4.	Chang, C-W: 1 article (10/2007)
5.	Kim, S W: 1 article (10/2007)
6.	Kim, W J: 1 article (10/2007)
7.	Yockman, J W: 1 article (10/2007)
8.	Christensen, Lane V: 1 article (09/2006)
9.	Jeong, Ji Hoon: 1 article (09/2006)
10.	Kim, Yong-Hee: 1 article (09/2006)

Related Diseases

1.	Neoplasms (Cancer) 09/12/2006 - "In this study, PEI-g-PEG-RGD/pCMV-sFlt-1 complexes are evaluated in terms of tumor growth inhibition in vivo. " 09/12/2006 - "As a result, tumor growth was inhibited in the PEI-g-PEG-RGD/pCMV-sFlt-1 injected group. " 09/12/2006 - "Anti-angiogenic inhibition of tumor growth by systemic delivery of PEI-g-PEG-RGD/pCMV-sFlt-1 complexes in tumor-bearing mice." 03/01/2011 - "In this study, we used PEI-g-PEG-RGD to deliver siRNA against VEGFR1 into tumor site. " 03/01/2011 - "Further, tumor growth profile was also investigated after systemic administration of PEI-g-PEG-RGD/siRNA complexes."
2.	Neoplasm Metastasis (Metastasis) 10/01/2007 - "To determine the effects of p2CMVIL2/msFlk1 in an experimental RENCA lung metastases model, therapeutic DNA was delivered systemically following complexation with the angiogenic endothelial-targeting polymer PEI-g-PEG-RGD. "

Related Drugs and Biologics

1.	Small Interfering RNA (siRNA)
2.	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)
3.	Polymers
4.	DNA (Deoxyribonucleic Acid)