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TAK-220

structure in first source

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - TAK-220: 3

Experts

1.	Kanzaki, Naoyuki: 2 articles (11/2005 - 08/2005)
2.	Takashima, Katsunori: 2 articles (11/2005 - 08/2005)
3.	Fujisawa, Jun-Ichi: 1 article (11/2005)
4.	Furuta, Rika A: 1 article (11/2005)
5.	Nishi, Toshiya: 1 article (11/2005)
6.	Nishikawa, Masao: 1 article (11/2005)
7.	Yamamoto, Yoshio: 1 article (11/2005)
8.	Baba, Masanori: 1 article (08/2005)
9.	Iizawa, Yuji: 1 article (08/2005)
10.	Miyake, Hiroshi: 1 article (08/2005)

Related Diseases

1.	Infections 08/01/2005 - "Thus, TAK-220 is a promising candidate for the treatment of HIV-1 infection." 11/01/2005 - "In this report, using a single-round infection assay with human CCR5 and its substitution mutants, we demonstrated that a new CCR5 antagonist, TAK-220, shares the putative interacting amino acid residues Asn252 and Leu255 in TM6 with TAK-779 but also requires the distinct residues Gly163 and Ile198 in TMs 4 and 5, respectively, for its inhibitory effect. "
2.	Neuralgia (Stump Neuralgia) 03/29/2023 - "The single intrathecal administration of CCL3 or CCL9 nAb, J113863, TAK-220, or AZD-5672 diminished neuropathic pain symptoms and enhanced morphine analgesia. "
3.	Body Weight (Weight, Body) 08/01/2005 - "At a dose of 5 mg/kg of body weight, TAK-220 showed oral bioavailabilities of 9.5 and 28.9% in rats and monkeys, respectively. "

Related Drugs and Biologics

1.	Morphine (MS Contin)
2.	Amino Acids
3.	N- (1- (3- (3,5- difluorophenyl)- 3- (4- methanesulfonylphenyl)propyl)piperidin- 4- yl)- N- ethyl- 2- (4- methanesulfonylphenyl)acetamide
4.	UCB 35625
5.	TAK 779

Related Therapies and Procedures

1.	Analgesia