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(R)- 2- (1- (1- naphthyl)ethyl- aminom- ethyl)indole

a positive allosteric modulator of the human Ca(2+) receptor

Also Known As:

calindol

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - (R)-2-(1-(1-naphthyl)ethyl-aminom-ethyl)indole: 3
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        (R)-2-(1-(1-naphthyl)ethyl-aminom-ethyl)indole: 3
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - (R)-2-(1-(1-naphthyl)ethyl-aminom-ethyl)indole: 3

Experts

1.	Li, Li: 1 article (10/2020)
2.	Li, Shu: 1 article (10/2020)
3.	Luan, Hairong: 1 article (10/2020)
4.	Meng, Jin: 1 article (10/2020)
5.	Song, Gaochen: 1 article (10/2020)
6.	Sun, Jian: 1 article (10/2020)
7.	Wang, Qi: 1 article (10/2020)
8.	Wei, Tao: 1 article (10/2020)
9.	Yang, Guohong: 1 article (10/2020)
10.	Yu, Yaquan: 1 article (10/2020)

Related Diseases

1.	Vascular Calcification 01/01/2012 - "The calcimimetic calindol prevents high phosphate-induced vascular calcification by upregulating matrix GLA protein."
2.	Myocardial Infarction 10/01/2020 - "Compared to the sham group, it was found that the expression levels of CaSR, caspase-3, cytoplasmic cytochrome C (cyt-C) and Bcl2-associated x (Bax), and the levels of Malondialdehyde (MDA) were significantly increased in both AMI and AMI + mESCs + Calindol groups with the development of myocardial infarction. "
3.	Fibrosis (Cirrhosis) 01/01/2020 - "The calindol-stimulated neutrophils from healthy rats promoted cardiomyocyte apoptosis and fibrosis of cardiac fibroblasts from healthy rats, which were inhibited by calhex-231. "

Related Drugs and Biologics

1.	Caspase 3 (Caspase-3)
2.	Cytochromes c (Cytochrome c)
3.	Phosphates (Orthophosphate)
4.	Malondialdehyde (Propanedial)
5.	Matrix Gla Protein
6.	N(1)- (4- chlorobenzoyl)- N(2)- (1- (1- naphthyl)ethyl)- 1,2- diaminocyclohexane
7.	salicylhydroxamic acid (SHAM)