HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

BKM-570

Also Known As:

2,3,4,5,6-pentafluorocinnamoyl-(o-2,6-dichlorobenzyl)-L-tyrosine-N-(4-amino-2,2,6,6-tetramethylpiperidyl)amide

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Halogenated Hydrocarbons: 42
    - Fluorinated Hydrocarbons: 4
      - Fluorocarbons: 1209
        BKM-570: 3
Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Cyclic Amino Acids: 3
    - Aromatic Amino Acids: 467
      - Tyrosine: 10509
        BKM-570: 3

Experts

1.	Gera, Lajos: 3 articles (08/2014 - 08/2005)
2.	Stewart, John M: 2 articles (12/2010 - 08/2005)
3.	Avdieiev, Stanislav: 1 article (08/2014)
4.	Havrylyuk, Dmytro: 1 article (08/2014)
5.	Hodges, Robert S: 1 article (08/2014)
6.	Kavsan, Vadym: 1 article (08/2014)
7.	Lesyk, Roman: 1 article (08/2014)
8.	Ribrag, Vincent: 1 article (08/2014)
9.	Vassetzky, Yegor: 1 article (08/2014)
10.	Bachvarov, Dimcho: 1 article (12/2010)

Related Diseases

1.	Endometrioid Carcinoma 12/01/2010 - "Here, we investigated BKM-570 cytotoxic effects in two EOC cell lines, derived from different EOC histopathologies: a clear cell carcinoma (TOV-21), and an endometrioid carcinoma (TOV-112). "
2.	Prostatic Neoplasms (Prostate Cancer) 08/01/2005 - "Due to its structure and biological activity, BKM-570 is an attractive lead compound for derivatization and evaluation for lung and prostate cancer drugs."
3.	Ovarian Neoplasms (Ovarian Cancer) 12/01/2010 - "We showed that BKM-570 effectively inhibited the growth of ovarian cancer cells, as its cytotoxic effects were comparable to those of cisplatin, and were independent of the functional status of BK receptors. " 12/01/2010 - "Strong cytotoxic effect of the bradykinin antagonist BKM-570 in ovarian cancer cells--analysis of the molecular mechanisms of its antiproliferative action."
4.	Glioma (Gliomas) 08/01/2014 - "We demonstrated a strong synergistic effect after combinatorial treatment by BKM-570 together with TMZ that drastically increased cytotoxic action of this drug in rat and human glioma cells. "
5.	Carcinoma (Carcinomatosis) 12/01/2010 - "Here, we investigated BKM-570 cytotoxic effects in two EOC cell lines, derived from different EOC histopathologies: a clear cell carcinoma (TOV-21), and an endometrioid carcinoma (TOV-112). "

Related Drugs and Biologics

1.	Bradykinin Receptor Antagonists
2.	Cisplatin (Platino)