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sodium 3,5- bis- ethoxycarbonyl- 2,6,dimethyl- 1,4- dihydropyridine- 4- carboxylate

a 1,4-dihydropyridine derivative that reduces DNA damage and stimulates DNA repair in human cells in vitro; structure in first source

Also Known As:

AV-153

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Dihydropyridines: 214
      - sodium 3,5-bis-ethoxycarbonyl-2,6,dimethyl-1,4-dihydropyridine-4-carboxylate: 2
    - Nicotinic Acids: 13
      - Niacin: 3030
        sodium 3,5-bis-ethoxycarbonyl-2,6,dimethyl-1,4-dihydropyridine-4-carboxylate: 2
- Heterocyclic Acids
  - Nicotinic Acids: 13
    - Niacin: 3030
      - sodium 3,5-bis-ethoxycarbonyl-2,6,dimethyl-1,4-dihydropyridine-4-carboxylate: 2

Experts

1.	Bisenieks, Egils: 1 article (09/2018)
2.	Bruvere, Imanta: 1 article (09/2018)
3.	Duburs, Gunars: 1 article (09/2018)
4.	Kalme, Zenta: 1 article (09/2018)
5.	Milkovic, Lidija: 1 article (09/2018)
6.	Ogle, Zaiga: 1 article (09/2018)
7.	Poikans, Janis: 1 article (09/2018)
8.	Tatzber, Franz: 1 article (09/2018)
9.	Velena, Astrida: 1 article (09/2018)
10.	Vukovic, Tea: 1 article (09/2018)

Related Diseases

1.	Osteoporosis 09/19/2018 - "Thiocarbatone III-1, E2-134-1 III-4, Carbatone II-1, AV-153 IV-1, and Diethone I could be considered as therapeutic agents for osteoporosis although further research is needed to elucidate their bioactivity mechanisms, in particular in respect to signaling pathways involving 4-hydroxynoneal and related second messengers of free radicals."
2.	Diabetes Mellitus 11/01/2016 - "Effects of an Antimutagenic 1,4-Dihydropyridine AV-153 on Expression of Nitric Oxide Synthases and DNA Repair-related Enzymes and Genes in Kidneys of Rats with a Streptozotocin Model of Diabetes Mellitus."

Related Drugs and Biologics

1.	Streptozocin (Streptozotocin)
2.	Nitric Oxide (Nitrogen Monoxide)
3.	Free Radicals
4.	Enzymes
5.	1,4-dihydropyridine (dihydropyridine)
6.	etidin