PD 140.548 N-methyl-D-glucamine

Networked: 2 relevant articles (0 outcomes, 2 trials/studies)

1.	Visceral Pain 01/01/2005 - "The aim of this study was to determine the influence of mechanically induced duodenal distension (DD) and PD 140.548 N-methyl-D-glucamine (a specific peptide antagonist of a CCK1 receptor) premedication on mechanographical reticulo-ruminal activity, animal general behaviour, catecholamines (CA) and the blood plasma cortisol levels, as well as the clinical symptoms of visceral pain induced by DD in sheep. " 08/01/2006 - "The aim of this study was to analyse the central action of PD 140.548 N-methyl-D-glucamine--a peptide antagonist of a specific peripheral type CCK receptor--on animal behaviour, catecholamines (CA) and cortisol concentration, as well as clinical symptoms of visceral pain induced by duodenal distension (DD). "
2.	Pain (Aches) 08/01/2006 - "Centrally administered PD 140.548 N-methyl-D-glucamine prevents the autonomic responses to duodenal pain in sheep." 01/01/2005 - "It is concluded that PD 140.548 N-methyl-D-glucamine--an antagonist of the central CCK1 receptor can be an effective analgesic agent in duodenal pain. "

1.	Peptides (Polypeptides)
2.	Hydrocortisone (Cortisol)
3.	Catecholamines
4.	Cholecystokinin Receptors (Cholecystokinin Receptor)
5.	Analgesics (Analgesic Drugs)

1.	Premedication