ceftobiprole medocaril

11/01/2008 - "Ceftobiprole medocaril has been evaluated in two phase III clinical trials for the treatment of complicated skin infections and skin structure infections. "
08/19/2023 - "tularensis infections in most animals that died prior to completing treatments (placebo animals and a rat treated with ceftobiprole medocaril), although levels of bacteria detected in the placebo samples were significantly elevated compared to the ceftobiprole-medocaril-treated group geometric mean. "
01/01/2016 - "Ceftobiprole medocaril (BAL-5788) for the treatment of complicated skin infections."
07/21/2023 - "The objective was to analyze the use of ceftobiprole medocaril (Cefto-M) in Spanish clinical practice in patients with infections in hospital or outpatient parenteral antimicrobial therapy (OPAT). "
08/19/2023 - "The efficacy of ceftobiprole medocaril against inhalational tularemia was evaluated in the Fischer 344 rat model of infection. "

09/01/2014 - "In patients with CAP, ceftobiprole medocaril was effective in those at risk for poor outcomes (pneumonia severity index ≥91, Pneumonia Patient Outcomes Research Team score IV-V or bacteraemic pneumonia). "
01/01/2007 - "Ceftobiprole medocaril is being studied in Phase III clinical trials for cSSSI, HAP and hospitalised community-acquired pneumonia (hCAP). "
01/01/2023 - "Ceftobiprole medocaril for the treatment of pneumonia."
09/01/2018 - "Ceftobiprole medocaril for the treatment of community-acquired pneumonia."
12/01/2016 - "Pharmacokinetics and Dosing of Ceftobiprole Medocaril for the Treatment of Hospital- and Community-Acquired Pneumonia in Different Patient Populations."

06/01/2012 - "Efficacy of ceftobiprole Medocaril against Enterococcus faecalis in a murine urinary tract infection model."

08/19/2023 - "Ceftobiprole medocaril is being explored as a medical countermeasure for the treatment of pneumonic tularemia. "
08/19/2023 - "Ceftobiprole Medocaril Is an Effective Post-Exposure Treatment in the Fischer 344 Rat Model of Pneumonic Tularemia."
08/19/2023 - "The efficacy of ceftobiprole medocaril against inhalational tularemia was evaluated in the Fischer 344 rat model of infection. "
08/19/2023 - "Overall, survival rates, body weights, and bacterial burdens consistently demonstrated that treatment with ceftobiprole medocaril is efficacious against otherwise fatal cases of pneumonic tularemia in the rat model."

04/01/2004 - "We studied the activity of BAL5788 in a mouse model of acute pneumococcal pneumonia. "
04/01/2004 - "Efficacy of BAL5788, a prodrug of cephalosporin BAL9141, in a mouse model of acute pneumococcal pneumonia."