N- (4- (2- ethyl- 4- (3- methylphenyl)- 1,3- thiazol- 5- yl)- 2- pyridyl)benzamide

01/01/2023 - "TAK-715 attenuated intervertebral disc degeneration in vitro and in vivo, suggesting that it might be an effective treatment for IDD."
01/01/2023 - "This study focused on the role and mechanism of the p38 inhibitor TAK-715 in intervertebral disc degeneration. "
01/01/2023 - "The role of TAK-715 in vivo was determined by acupuncture-induced intervertebral disc degeneration. "
01/01/2023 - "TAK-715 alleviated IL-1β-induced apoptosis and ECM degradation in nucleus pulposus cells and attenuated intervertebral disc degeneration ex vivo and in vivo."
01/01/2023 - "In a rat tail model, TAK-715 ameliorates puncture-induced disc degeneration based on MRI and histopathology evaluations. "