|1.||Leal, Paulo César: 3 articles (05/2015 - 12/2011)|
|2.||Hirsch, Emilio: 3 articles (12/2010 - 03/2008)|
|3.||Chen, Li-juan: 3 articles (06/2010 - 09/2009)|
|4.||Luo, You-fu: 3 articles (06/2010 - 09/2009)|
|5.||Chen, Zhi-zhi: 3 articles (06/2010 - 09/2009)|
|6.||Rommel, Christian: 2 articles (01/2012 - 03/2008)|
|7.||Rückle, Thomas: 2 articles (01/2012 - 03/2008)|
|8.||Wu, Xiao-Hua: 2 articles (07/2011 - 09/2009)|
|9.||Hu, Xiao-Hong: 2 articles (07/2011 - 09/2009)|
|10.||Song, Li-Fang: 2 articles (07/2011 - 09/2009)|
|1.||Body Weight (Weight, Body)
07/01/2011 - "Compared with ISO group, histological examination of the heart showed that AS605240 significantly relieved the rat cardiac fibrosis and reduced heart/body weight ratios in experimental cardiac fibrosis (P < 0.05). "
09/01/2009 - "Histological examination of the heart showed that AS605240 significantly relieved the murine myocarditis and reduced heart/body weight ratios in experimental autoimmune myocarditis (EAM) (P< 0.01). "
|2.||Pulmonary Fibrosis (Hamman Rich Syndrome)
06/25/2010 - "These findings also suggest that PI3Kgamma may be a useful target in treating inflammation diseases and AS605240 may represent a promising novel agent for the future therapy of pulmonary fibrosis."
06/25/2010 - "Our findings illustrated that AS605240 was effective for preventing pulmonary fibrosis by suppressing inflammatory cells recruitment and production of inflammatory cytokines. "
06/25/2010 - "In this study, we investigated the protective effect of AS605240 on bleomycin-induced pulmonary fibrosis in rats. "
06/25/2010 - "A phosphoinositide 3-kinase-gamma inhibitor, AS605240 prevents bleomycin-induced pulmonary fibrosis in rats."
09/04/2009 - "Orally administration of AS605240 significantly improved survival, decreased the serum levels of alanine aminotransaminase (ALT), prevented inflammatory infiltration to liver in ConA-induced hepatitis. "
09/04/2009 - "In present study we investigated the therapeutic efficiency of AS605240, a selective PI3Kgamma inhibitor, on hepatitis and liver fibrosis in murine models induced by concanavalin A (ConA). "
03/11/2008 - "Here, we demonstrate that a specific PI3Kgamma inhibitor (AS605240) is effective in murine models of established atherosclerosis. "
01/01/2010 - "5-Quinoxilin-6-methylene-1,3-thiazolidine-2,4-dione (AS605240), a potent PI3Kgamma inhibitor, has been reported to ameliorate chronic inflammatory disorders including rheumatoid arthritis, systemic lupus erythematosus, and atherosclerosis. "
03/11/2008 - "Intraperitoneal administration of AS605240 (10 mg/kg daily) significantly decreased early atherosclerotic lesions in apolipoprotein E-deficient mice and attenuated advanced atherosclerosis in low-density lipoprotein receptor-deficient mice. "
|2.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|5.||Antimony Sodium Gluconate (Sodium, Stibogluconate)
|2.||Heterologous Transplantation (Xenotransplantation)