HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

bisnaphthalimidopropyl spermine

putative cytostatic agent against Leishmania infantum; structure in first source

Also Known As:

BNIPSpm

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Polyamines: 3918
    - Spermine: 1076
      - bisnaphthalimidopropyl spermine: 4
  - Biogenic Amines: 992
    - Biogenic Polyamines: 11
      - Putrescine: 919
        Spermidine: 1153
        Spermine: 1076
        bisnaphthalimidopropyl spermine: 4
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Quinolones: 2938
        bisnaphthalimidopropyl spermine: 4

Experts

1.	Milne, Lesley: 2 articles (12/2011 - 01/2005)
2.	Bestwick, Charles Stuart: 1 article (12/2011)
3.	Duthie, Susan J: 1 article (12/2011)
4.	Kong Thoo Lin, Paul: 1 article (12/2011)
5.	Ralton, Lynda D: 1 article (12/2011)
6.	Cordeiro-da-Silva, A: 1 article (05/2005)
7.	Lin, P K T: 1 article (05/2005)
8.	Ouaissi, A: 1 article (05/2005)
9.	Tavares, J: 1 article (05/2005)
10.	Tomás, A: 1 article (05/2005)

Related Diseases

1.	Visceral Leishmaniasis (Kala Azar) 05/01/2005 - "In the present study, we have investigated the effect of three polyamine derivatives, (namely bis-naphthalimidopropyl putrescine (BNIPPut), spermidine (BNIPSpd) and spermine (BNIPSpm)), on the proliferative stages of Leishmania infantum, the causative agent of visceral leishmaniasis in the Mediterranean basin. "
2.	Breast Neoplasms (Breast Cancer) 01/01/2005 - "Their cytotoxic properties were evaluated against breast cancer MCF 7 cells and compared with bisnaphthalimidopolyamines BNIPSpd and BNIPSpm. " 07/31/2001 - "Bis-naphthalimidopropyl spermidine (BNIPSpd), spermine (BNIPSpm) and oxa-spermine (BNIPOSpm) showed high in vitro cytotoxicity against human breast cancer MCF-7 cells with IC(50) values of 1.38, 2.91 and 8.45 microM, respectively. "
3.	Colonic Neoplasms (Colon Cancer) 12/01/2011 - "Here, extending earlier work on bisnaphthalimidopropylspermidine (BNIPSpd)-induced apoptosis in colon adenocarcinoma Caco-2 cells, we compare the cytotoxicity and genotoxicity of BNIPSpd relative to the spermine and oxaspermine derivatives, bisnaphthalimidopropylspermine (BNIPSpm) and bisnaphthalimidopropyloxaspermine (BNIPOSpm). "

Related Drugs and Biologics

1.	bisnaphthalimidopropylspermidine
2.	Spermine
3.	Spermidine
4.	Putrescine
5.	Polyamines
6.	bisnaphthalimidopropyl putrescine