fenbuconazole

fenbuconazole is a formulant in the fungicide Enable; structure in first source

Also Known As:

(RS)-4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butyrontrile; alpha(2-(4-chlorophenyl)ethyl)-alpha-phenyl-1H-1,2,4-triazole-1-propanentrile; 1H-1,2,4-Triazole-1-propanenitrile, alpha-(2-(4-chlorophenyl)ethyl)-alpha-phenyl-

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chen, Siying: 1 article (01/2022)
2.	Martyniuk, Christopher J: 1 article (01/2022)
3.	Qin, Yingju: 1 article (01/2022)
4.	Wang, Jia: 1 article (01/2022)
5.	Wang, Shuo: 1 article (01/2022)
6.	Wang, Xiaohong: 1 article (01/2022)
7.	Wen, Yang: 1 article (01/2022)
8.	Yan, Xiliang: 1 article (01/2022)
9.	Zhao, Yuanhui: 1 article (01/2022)
10.	Zhu, Di: 1 article (01/2022)

Related Diseases

1.	Neoplasms (Cancer) 07/15/2006 - "The aim of this study was to evaluate whether the mode of action for liver tumor formation by fenbuconazole is similar to that of phenobarbital. "
2.	Mitochondrial Diseases (Mitochondrial Disease) 01/01/2022 - "Fenbuconazole reduced mitochondrial membrane potential and reduced the activities of mitochondrial Complex II and III. Transcript levels of both sdhc and cyc1, each related to Complex II and III, were also altered in expression by fenbuconazole exposure, consistent with mitochondrial dysfunction in embryos. "
3.	Infections 06/01/2008 - "The activity of fenbuconazole and azoxystrobin applied to blueberry flowers at different phenological stages against subsequent gynoecial infection by the mummy berry fungus Monilinia vaccinii-corymbosi was evaluated. "
4.	Hypertrophy 07/15/2006 - "Treatment of CD1 mice with 0, 20, 60, 180 or 1300 ppm fenbuconazole for up to 4 weeks caused a dose-dependent increase in liver weight that was associated with centrilobular hepatocellular hypertrophy, cytoplasmic eosinophilia and panlobular hepatocellular vacuolation, as well as an initial increase in the cell proliferation labeling index. "
5.	Eosinophilia 07/15/2006 - "Treatment of CD1 mice with 0, 20, 60, 180 or 1300 ppm fenbuconazole for up to 4 weeks caused a dose-dependent increase in liver weight that was associated with centrilobular hepatocellular hypertrophy, cytoplasmic eosinophilia and panlobular hepatocellular vacuolation, as well as an initial increase in the cell proliferation labeling index. "

Related Drugs and Biologics

1.	Phenobarbital (Luminal)
2.	Triazoles
3.	Cytochrome P-450 Enzyme System (Cytochrome P450)
4.	azoxystrobin