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VX-944

small molecule selective noncompetitive inhibitor of both isoforms of human inosine monophosphate dehydrogenase; induces apoptosis in multiple myeloma cells primarily via caspase-independent AIF/Endo G pathway
Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Hamasaki, Makoto: 1 article (09/2005)
2. Roccaro, Aldo M: 1 article (09/2005)
3. Tamura, Kazuo: 1 article (09/2005)
4. Ishitsuka, Kenji: 1 article (09/2005)
5. Jain, Jugnu: 1 article (09/2005)
6. Anderson, Kenneth C: 1 article (09/2005)
7. Yasui, Hiroshi: 1 article (09/2005)
8. Raje, Noopur: 1 article (09/2005)
9. Kumar, Shaji: 1 article (09/2005)
10. Podar, Klaus: 1 article (09/2005)

Related Diseases

1. Multiple Myeloma

Related Drugs and Biologics

1. Oxidoreductases
2. Inosine Monophosphate (IMP)