hydrocinnamate- cyclo(ornithyl- prolyl- cyclohexylalanyl- tryptophyl- arginyl)

Subscribe to Selected New Research on hydrocinnamate-cyclo(ornithyl-prolyl-cyclohexylalanyl-tryptophyl-arginyl)

1 relevant articles (1 outcomes, 1 trials/studies) found for this Bio-Agent

Also Known As:

(HC)-(OP(D-Cha)WR); HC-(OPChaWR)

Relationship Network

Bio-Agent Context: Research Results

Polycyclic Compounds: 58

Macrocyclic Compounds: 1

Cyclic Peptides: 41

hydrocinnamate-cyclo(ornithyl-prolyl-cyclohexylalanyl-tryptophyl-arginyl): 1

Amino Acids, Peptides, and Proteins

Peptides: 16074

Cyclic Peptides: 41

hydrocinnamate-cyclo(ornithyl-prolyl-cyclohexylalanyl-tryptophyl-arginyl): 1

Related Diseases

1.	Colitis 08/01/2005 - "This study tested the efficacy and potency of a new C5a antagonist, hydrocinnamate (HC)-[OP(d-Cha)WR], which has limited intestinal lumenal metabolism, in this model of colitis" 08/01/2005 - "These studies suggest that resistance to intestinal metabolism by HC-[OP(d-Cha)WR] may result in increased local concentrations of the drug in the colon, thus affording efficacy with markedly lower oral doses than AcF-[OP(d-Cha)WR] against TNBS-colitis" 08/01/2005 - "One metabolically stable analog, HC-[OP(d-Cha)WR], was then evaluated pharmacokinetically and investigated at a range of doses (0.03-10 mg/kg/day p.o.) in the 8-day rat TNBS-colitis model, against the comparator drug AcF-[OP(d-Cha)WR]" 08/01/2005 - "However, in the rat TNBS-colitis model, HC-[OP(d-Cha)WR] was effective at reducing mortality, colon edema, colon macroscopic scores, and increasing food consumption and body weights, at 10- to 30-fold lower oral doses than AcF-[OP(d-Cha)WR]" Get all the results and reference details, order at left...
2.	Edema 08/01/2005 - "However, in the rat TNBS-colitis model, HC-[OP(d-Cha)WR] was effective at reducing mortality, colon edema, colon macroscopic scores, and increasing food consumption and body weights, at 10- to 30-fold lower oral doses than AcF-[OP(d-Cha)WR]" Get all the results and reference details, order at left...
3.	Body Weight (Weight, Body) 08/01/2005 - "However, in the rat TNBS-colitis model, HC-[OP(d-Cha)WR] was effective at reducing mortality, colon edema, colon macroscopic scores, and increasing food consumption and body weights, at 10- to 30-fold lower oral doses than AcF-[OP(d-Cha)WR]" Get all the results and reference details, order at left...
3 Diseases and 1 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	AcPhe(ornithine- Pro- cyclohexylamine- Trp- Arg)
2.	Dihydrotachysterol (AT 10)
2 Drugs and Important Bio-Agents and 1 more articles analyzed in the Research Interface, order at left...

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