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Pep-1 peptide

a synthetic cell-penetrating peptide; amino acid sequence in first source

Also Known As:

Chariot peptide; Pep-1 protein

Networked: 8 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Ethylamines: 5
    - Mercaptoethylamines
      - Cysteamine: 1042
        Pep-1 peptide: 8
- Sulfur Compounds: 278
  - Sulfhydryl Compounds: 4168
    - Mercaptoethylamines
      - Cysteamine: 1042
        Pep-1 peptide: 8
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Pep-1 peptide: 8

Experts

1.	Choi, Young Wook: 3 articles (12/2019 - 12/2010)
2.	Choi, Soo Young: 3 articles (01/2017 - 10/2014)
3.	Hwang, Hyun Sook: 3 articles (01/2017 - 10/2014)
4.	Kim, Hyun Ah: 2 articles (01/2017 - 07/2015)
5.	Park, In Young: 2 articles (01/2017 - 07/2015)
6.	Kim, Dae Won: 2 articles (07/2015 - 10/2014)
7.	Kang, Mean Hyung: 2 articles (01/2013 - 12/2010)
8.	Kang, Myung Joo: 2 articles (01/2013 - 12/2010)
9.	Park, Sang Han: 2 articles (01/2013 - 12/2010)
10.	Chang, In Ho: 1 article (12/2019)

Related Diseases

1.	Glioma (Gliomas) 10/01/2017 - "Pep-1 peptide-functionalized liposome to enhance the anticancer efficacy of cilengitide in glioma treatment."
2.	Atopic Dermatitis (Atopic Eczema) 12/15/2010 - "Pep-1 peptide-conjugated elastic liposomal formulation of taxifolin glycoside for the treatment of atopic dermatitis in NC/Nga mice." 12/15/2010 - "In order to develop topical preparations of taxifolin glycoside (TXG) for the treatment of atopic dermatitis (AD), formulations of Pep-1 peptide-conjugated elastic liposomes (Pep1-EL) were examined for their in vitro skin permeation profile and in vivo therapeutic efficacy. "
3.	Neoplasms (Cancer) 01/01/2018 - "In this study, we developed a dual targeted delivery system with paclitaxel (PTX) and SPION co-loaded PLGA nanoparticles, modified with Pep-1 peptide (Pep-NP-SPION/PTX), to achieve magnetic targeting and active targeting for tumor treatment. " 01/01/2013 - "Folic acid-tethered Pep-1 peptide-conjugated liposomal nanocarrier for enhanced intracellular drug delivery to cancer cells: conformational characterization and in vitro cellular uptake evaluation." 01/01/2013 - "A novel dual ligand-modified liposome, folic acid-tethered Pep-1 peptide-conjugated liposomal nanocarrier (FP-Lipo), was designed to overcome the nonselectivity of conventional penetrating peptide-tagged nanoparticulates and to provide the advantage of selective targeting of the folic acid receptor, which is frequently overexpressed on epithelial cancer cells. "
4.	Edema (Dropsy) 01/01/2017 - "In this study, we investigated whether PEP-1-GRX-1, a fusion protein of GRX-1 and PEP-1 peptide, a PTD, could suppress catabolic responses in primary human articular chondrocytes and a mouse carrageenan-induced paw edema model. "
5.	Arthritis (Polyarthritis) 07/01/2015 - "In this study, we investigated the ability of PEP-1-FK506BP12, consisting of FK506BP12 fused to the protein transduction domain PEP-1 peptide, to suppress catabolic responses in primary human chondrocytes and in a mouse carrageenan-induced paw arthritis model. "

Related Drugs and Biologics

1.	Liposomes (Liposome)
2.	Glycosides
3.	Cilengitide
4.	taxifolin
5.	Proteins (Proteins, Gene)
6.	Carrageenan
7.	Paclitaxel (Taxol)
8.	Folic Acid (Vitamin M)
9.	Cell Wall Skeleton
10.	Peptides (Polypeptides)