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indole-2-carboxylate

structure in first source

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - indole-2-carboxylate: 4

Experts

1.	Araújo, Thiago S L: 1 article (04/2017)
2.	Medeiros, Jand Venes R: 1 article (04/2017)
3.	Nicolau, Lucas A D: 1 article (04/2017)
4.	Nogueira, Kerolayne M: 1 article (04/2017)
5.	Sousa, Francisca Beatriz M: 1 article (04/2017)
6.	Sousa, Nayara A: 1 article (04/2017)
7.	Souza, Luan Kelves M: 1 article (04/2017)
8.	Ji, Xing-yue: 1 article (08/2014)
9.	Jin, Jie: 1 article (08/2014)
10.	Li, Zhuo-rong: 1 article (08/2014)

Related Diseases

1.	Stroke (Strokes) 10/01/2001 - "After the identification of GV150526, the indole-2-carboxylate template was further explored in order to identify novel potential anti-stroke agents. " 09/09/1999 - "A series of analogues of the indole-2-carboxylate GV150526, currently in clinical trials as a potential neuroprotective agent for the control of the cerebral damage after stroke onset, was designed based on previous studies dealing with the electronic features of the north-east region of the glycine binding site associated with the NMDA receptor. "
2.	Neoplasms (Cancer) 08/18/2014 - "Based on the chemical structure of Pyrroloquinoline quinone (PQQ), a novel class of indole-2-carboxylate derivatives was designed, synthesized and assayed for antiproliferative activity in cancer cells in vitro. "
3.	Edema (Dropsy) 04/01/2017 - "Histological analysis revealed that pretreatment with d-cysteine decreased hemorrhagic damage, edema, and the loss of the epithelium, whereas the administration of indole-2-carboxylate reversed these effects. "

Related Drugs and Biologics

1.	3- (2- ((phenylamino)carbonyl)ethenyl)- 4,6- dichloroindole- 2- carboxylic acid
2.	Neuroprotective Agents
3.	N-Methyl-D-Aspartate Receptors (NMDA Receptors)
4.	Glycine (Aminoacetic Acid)
5.	PQQ Cofactor (Pyrroloquinoline Quinone)
6.	Cysteine (L-Cysteine)