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2-isopropylmalic acid

chelates aluminum(III); structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Hydroxy Acids: 94
    - Malates
      - 2-isopropylmalic acid: 1
  - Acyclic Acids
    - Dicarboxylic Acids: 108
      - Malates
        2-isopropylmalic acid: 1

Experts

1.	Checkley, William: 1 article (12/2016)
2.	Christians, Uwe: 1 article (12/2016)
3.	Deza, Maria P: 1 article (12/2016)
4.	Hansel, Nadia N: 1 article (12/2016)
5.	Klawitter, Jelena: 1 article (12/2016)
6.	Klawitter, Jost: 1 article (12/2016)
7.	Pollard, Suzanne L: 1 article (12/2016)
8.	Romero, Karina M: 1 article (12/2016)
9.	Wise, Robert A: 1 article (12/2016)

Related Diseases

1.

Asthma (Bronchial Asthma)

12/01/2016 - "Moreover, a combination of 2-isopropylmalic acid and betaine strongly discriminated between children with asthma (2-isopropylmalic acid ≤ 13 077 normalized counts/second) and controls (2-isopropylmalic acid > 13 077 normalized counts/second and betaine ≤ 16 47 121 normalized counts/second). "
12/01/2016 - "A statistical comparison of targeted metabolites between children with asthma (n = 50) and healthy controls (n = 49) revealed distinct patterns in relative concentrations of several metabolites: children with asthma had approximately 40-50% lower relative concentrations of ascorbic acid, 2-isopropylmalic acid, shikimate-3-phosphate, and 6-phospho-d-gluconate when compared to children without asthma, and 70% lower relative concentrations of reduced glutathione (all p < 0.001 after Bonferroni correction). "

Related Drugs and Biologics

1.	Glutathione (Reduced Glutathione)
2.	Betaine (C.B.B.)
3.	Ascorbic Acid (Vitamin C)
4.	shikimic acid-3-phosphate