(5- (2- methoxy- 5- chloro- 5- phenyl)furan- 2- ylcarbonyl)guanidine

Subscribe to Selected New Research on (5-(2-methoxy-5-chloro-5-phenyl)furan-2-ylcarbonyl)guanidine

5 relevant articles (2 outcomes, 0 trials/studies) found for this Bio-Agent

Description: KR-32570 possesses potent cardioprotective effects in perfused rat hearts, and its effects may be mediated by inhibition of NHE-1, preservation of high-energy phosphates, and inhibition of lipid peroxidation

Also Known As:

(5-(2-methoxy-5-chlorophenyl)furan-2-ylcarbonyl)guanidine; KR-32570

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 40

Amidines: 8

Guanidines: 11

(5-(2-methoxy-5-chloro-5-phenyl)furan-2-ylcarbonyl)guanidine: 5

Experts

1.	Yi, Kyu Yang: 3 articles (11/2005 - 03/2005)
2.	Lee, Sunkyung: 3 articles (11/2005 - 03/2005)
3.	Lee, Sunghou: 2 articles (10/2005 - 03/2005)
4.	Lee, Byung Ho: 2 articles (10/2005 - 03/2005)
5.	Yoo, Sung-eun: 2 articles (10/2005 - 03/2005)
6.	Yoo, Sung Eun: 1 article (11/2005)
7.	Kim, Mi Jeong: 1 article (11/2005)
8.	Moon, Chang-Hyun: 1 article (11/2005)
9.	Kim, Mi-Young: 1 article (11/2005)
10.	Jung, Yi-Sook: 1 article (11/2005)

Related Diseases

1.	Ischemia 03/28/2005 - "KR-32570 (1-10 microM) significantly decreased the concentration of 8-iso-prostaglandin F(2 alpha), a reliable marker for oxidant stress, in perfusates from rat hearts subjected to ischemia and reperfusion" 03/28/2005 - "Effects of KR-32570, a new Na+/H+ exchanger inhibitor, on functional and metabolic impairments produced by global ischemia and reperfusion in the perfused rat heart." 10/31/2005 - "Taken together, these results indicate that KR-32570 significantly reduced the myocardial infarction and incidence of arrhythmias induced by ischemia and reperfusion in rats and dogs, without affecting hemodynamic profiles" 03/28/2005 - "In isolated perfused rat hearts subjected to 30-min ischemia/30-min reperfusion, KR-32570 (1-10 microM) significantly and concentration dependently improved cardiac contractile function and severe contracture in conjunction with causing a marked reduction in lactate dehydrogenase release" 10/31/2005 - "Effects of KR-32570, a new sodium hydrogen exchanger inhibitor, on myocardial infarction and arrhythmias induced by ischemia and reperfusion." Get all the results and reference details, order at left...
2.	Ventricular Premature Complexes (Premature Ventricular Contraction) 10/31/2005 - "KR-32570 dose-dependently decreased the incidence of premature ventricular contraction, ventricular tachycardia or ventricular fibrillation induced by ischemia and reperfusion in rats" Get all the results and reference details, order at left...
3.	Ventricular Tachycardia 10/31/2005 - "KR-32570 dose-dependently decreased the incidence of premature ventricular contraction, ventricular tachycardia or ventricular fibrillation induced by ischemia and reperfusion in rats" Get all the results and reference details, order at left...
4.	Ventricular Fibrillation 10/31/2005 - "KR-32570 dose-dependently decreased the incidence of premature ventricular contraction, ventricular tachycardia or ventricular fibrillation induced by ischemia and reperfusion in rats" Get all the results and reference details, order at left...
5.	Contracture 03/28/2005 - "In isolated perfused rat hearts subjected to 30-min ischemia/30-min reperfusion, KR-32570 (1-10 microM) significantly and concentration dependently improved cardiac contractile function and severe contracture in conjunction with causing a marked reduction in lactate dehydrogenase release" Get all the results and reference details, order at left...
11 Diseases and 5 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	L-Lactate Dehydrogenase (Lactate Dehydrogenase)
2.	Guanidine (Guanidine Nitrate)
3.	furan
4.	Cytochromes c (Cytochrome c)
5.	Sodium-Hydrogen Antiporter
6.	cariporide
6 Drugs and Important Bio-Agents and 5 more articles analyzed in the Research Interface, order at left...

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License details >>

Price:

$490.00 access via web interface, 1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m", 1 year subscription

Proceed to Checkout >>