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4-acetyltropolone

4-acetyltropolone had clear antifungal activity against seven kinds of plant-pathogenic fungi

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Alicyclic Hydrocarbons: 1
      - Cycloparaffins: 6
        Cycloheptanes
        Tropolone: 44
        4-acetyltropolone: 1

Experts

1.	Fukui, Toru: 1 article (10/2004)
2.	Inamori, Yoshihiko: 1 article (10/2004)
3.	Ishida, Nakao: 1 article (10/2004)
4.	Matsumura, Eiko: 1 article (10/2004)
5.	Morita, Yasuhiro: 1 article (10/2004)
6.	Ohe, Tatsuhiko: 1 article (10/2004)
7.	Okabe, Toshihiro: 1 article (10/2004)

Related Diseases

1.

Lymphoid Leukemia

10/01/2004 - "At 48 h after treatment, gamma-thujaplicin and 4-acetyltropolone at 0.63 microg/ml inhibited cell growth of murine P388 lymphocytic leukemia by 85% and 65%, respectively. "
10/01/2004 - "In particular, beta-dolabrin and 4-acetyltropolone showed strong antifungal activity against Pythium aphanidermatum IFO 32440, with minimum inhibitory concentration (MIC) values of 6.0 microg/ml. Secondly, beta-dolabrin, gamma-thujaplicin and 4-acetyltropolone had obvious growth-inhibitory effect on two kinds of Legionella sp. 4-Acetyltropolone especially had strong antibacterial activity toward Legionella pneumophila SG 1, and its MIC value was 3.1 microg/ml. These three compounds showed cytotoxic effects against murine P388 lymphocytic leukemia cell line in vitro. "

Related Drugs and Biologics

1.	beta-dolabrin
2.	2-hydroxy-5-isopropyl- 2,4,6-cycloheptatrienone

Related Therapies and Procedures

1.	Aftercare (After-Treatment)