FR255031

matrix metalloproteinase inhibitor; structure in first source

Also Known As:

2-((7S)-7-(5-(4-ethylphenyl)-2-thienyl)-1,1-dioxido-4-(2-pyridinylcarbonyl)hexahydro-1,4-thiazepin-7-yl)-N-hydroxyacetamide

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Body Weight (Weight, Body) 01/01/2005 - "FR255031 at a dose of 100 mg kg(-1) also had statistically significant effects on bone destruction and pannus formation and on the recovery of body weight loss on day 28. "
2.	Experimental Arthritis 01/01/2005 - "We studied the effect of FR255031 and Trocade, an inhibitor of collagenase and MMP-14, on a rat collagen-induced arthritis (CIA) model. " 01/01/2005 - "Prevention of progressive joint destruction in collagen-induced arthritis in rats by a novel matrix metalloproteinase inhibitor, FR255031."

1.	Matrix Metalloproteinase Inhibitors
2.	Collagenases (Collagenase)