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bolinaquinone

a marine sesquiterpenoid from sponge Dysidea sp. with anti-inflammatory activity; structure in first source

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - bolinaquinone: 2

Experts

1.	Payá, Miguel: 2 articles (05/2005 - 03/2003)
2.	Alcaraz, Maria José: 1 article (05/2005)
3.	Busserolles, Jérôme: 1 article (05/2005)
4.	D'Auria, Maria Valeria: 1 article (05/2005)
5.	Gomez-Paloma, Luigi: 1 article (05/2005)
6.	D'auria, Maria Valeria: 1 article (03/2003)
7.	Giannini, Clelia: 1 article (03/2003)
8.	Lucas, Rut: 1 article (03/2003)

Related Diseases

1.	Inflammation (Inflammations) 05/15/2005 - "Protection against 2,4,6-trinitrobenzenesulphonic acid-induced colonic inflammation in mice by the marine products bolinaquinone and petrosaspongiolide M."
2.	Osteophyte 03/01/2003 - "Additionally, bolinaquinone inhibited inducible nitric oxide synthase expression and reduced the degree of bone resorption, soft tissue swelling, and osteophyte formation."
3.	Bone Resorption 03/01/2003 - "Additionally, bolinaquinone inhibited inducible nitric oxide synthase expression and reduced the degree of bone resorption, soft tissue swelling, and osteophyte formation."
4.	Experimental Arthritis 03/01/2003 - "Moreover, bolinaquinone was able to reduce the inflammatory response of adjuvant arthritis by inhibiting PGE(2), NO, and TNF-alpha production in paw homogenates without affecting PGE(2) levels in the stomach. "

Related Drugs and Biologics

1.	Acids
2.	petrosaspongiolide m
3.	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)
4.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
5.	Prostaglandins E