|1.||Abdullah, Mohd Puad: 4 articles (07/2015 - 01/2013)|
|2.||Yeap, Swee Keong: 4 articles (07/2015 - 01/2013)|
|3.||Abu, Nadiah: 4 articles (07/2015 - 01/2013)|
|4.||Alitheen, Noorjahan Banu: 4 articles (07/2015 - 01/2013)|
|5.||Akhtar, M Nadeem: 4 articles (07/2015 - 01/2013)|
|6.||Omar, Abdul Rahman: 4 articles (07/2015 - 01/2013)|
|7.||Zi, Xiaolin: 3 articles (12/2015 - 04/2005)|
|8.||Lim, Kian Lam: 2 articles (01/2015 - 01/2014)|
|9.||Zulfadli, Aimi Jamil: 2 articles (01/2015 - 01/2014)|
|10.||Ho, Wan Yong: 2 articles (01/2014 - 01/2013)|
12/08/2015 - "Flavokawain A induces deNEDDylation and Skp2 degradation leading to inhibition of tumorigenesis and cancer progression in the TRAMP transgenic mouse model."
01/01/2015 - "Overall, flavokawain A has the potential to not only enhance antitumor immunity, but also prevents the inflammatory process in a cancer-prone microenvironment. "
01/01/2015 - "Apart from that, flavokawain A also decreased the weight and volume of the tumor, and managed to induce apoptosis in them. "
01/01/2014 - "The extract of the roots of this plant contains a variety of interesting molecules including Flavokawain A and this molecule is known to have anti-cancer properties. "
01/01/2013 - "It has also been revealed that both flavokawain A and B are involved in the induction of cell cycle arrest in several cancer cell lines. "
|2.||Breast Neoplasms (Breast Cancer)
01/01/2015 - "Thus, this study aimed to elucidate the basic mechanism as to how flavokawain A regulates and enhance the immune system as well as impeding the inflammatory process in breast cancer-challenged mice. "
01/01/2015 - "The immunomodulatary effects and the anti-inflammatory effects of flavokawain A in a breast cancer murine model have not been studied yet. "
01/01/2015 - "In Vivo Anti-Tumor Effects of Flavokawain A in 4T1 Breast Cancer Cell-Challenged Mice."
|4.||Urinary Bladder Neoplasms (Bladder Cancer)
11/01/2008 - "This selectivity of flavokawain A for inducing a G(2)-M arrest in p53-defective cells deserves further investigation as a new mechanism for the prevention and treatment of bladder cancer."
11/01/2008 - "In contrast, flavokawain A induced a G(2)-M arrest in six p53 mutant-type, high-grade bladder cancer cell lines (T24, UMUC3, TCCSUP, 5637, HT1376, and HT1197). "
04/15/2005 - "Because both X-linked inhibitor of apoptosis and survivin are main factors for apoptosis resistance and are overexpressed in bladder tumors, our data suggest that flavokawain A may have a dual efficacy in induction of apoptosis preferentially in bladder tumors. "
11/01/2008 - "Effects of the kava chalcone flavokawain A differ in bladder cancer cells with wild-type versus mutant p53."
04/15/2005 - "Finally, the anticarcinogenic effect of flavokawain A was evident in its inhibitory growth of bladder tumor cells in a nude mice model (57% of inhibition) and in soft agar."
|3.||bcl-2-Associated X Protein (bcl 2 Associated X Protein)
|5.||Cytochromes c (Cytochrome c)
|6.||NF-kappa B (NF-kB)