HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

NAc- Sar- Gly- Val- (d- allo- Ile)- Thr- Nva- Ile- Arg- ProNEt (ABT 510)

has antiangiogenic and antineoplastic activity; structure in first source
Also Known As:
ABT 510; ABT-510; ABT510; N-acetyl-sarcosyl-glycyl-valyl-alloisoleucyl-threonyl-norvalyl-isoleucyl-arginyl-proline ethylamide
Networked: 25 relevant articles (6 outcomes, 15 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Henkin, Jack: 8 articles (03/2010 - 10/2004)
2. Knight, Raymond A: 4 articles (12/2008 - 08/2005)
3. Humerickhouse, Rod A: 4 articles (12/2008 - 08/2005)
4. Gladson, Candece L: 2 articles (03/2010 - 03/2007)
5. Petrik, Jim: 2 articles (03/2010 - 01/2009)
6. Greenaway, James: 2 articles (03/2010 - 01/2009)
7. Mendelson, David: 2 articles (12/2008 - 12/2008)
8. Carr, Robert A: 2 articles (12/2008 - 08/2005)
9. Gordon, Gary B: 2 articles (12/2008 - 11/2007)
10. Qian, Jiang: 2 articles (12/2008 - 11/2007)

Related Diseases

1. Neoplasms (Cancer)
2. Melanoma (Melanoma, Malignant)
06/01/2007 - "A phase II study of ABT-510 (thrombospondin-1 analog) for the treatment of metastatic melanoma."
06/01/2007 - "A 2-stage phase II clinical trial was conducted to assess the clinical efficacy, safety, and pharmacodynamic effects (angiogenesis and immunity) of ABT-510 in patients with stage IV melanoma. "
06/01/2007 - "We conducted a phase II trial evaluating the clinical efficacy of ABT-510 and its effects on biomarkers of angiogenesis and immunity in patients with metastatic melanoma (MM). "
04/21/2005 - "Previous studies had shown that ABT-510 was effective in inhibiting the outgrowth of murine melanoma metastases in syngeneic mice and in blocking the growth of human bladder carcinoma implanted in nude mice. "
01/01/2006 - "This issue focuses on the following selection of drugs: ABT-510, adalimumab, alefacept, ambrisentan, aminolevulinic acid methyl ester, armodafinil, aselizumab, asenapine maleate, azelnidipine; Bevacizumab, bexarotene, bimosiamose, biphasic insulin aspart, bortezomib, bosentan, BQ-123; C340, cannabidiol, caspofungin acetate, CC-4047, certolizumab pegol, cetuximab, ciclesonide, cilansetron, Cypher; Dabigatran etexilate, darbepoetin alfa, darifenacin hydrobromide, desloratadine, dexosome vaccine (melanoma), dimethyl fumarate, dronabinol/cannabidiol, drospirenone, drospirenone/estradiol, drotrecogin alfa (activated), duloxetine hydrochloride, dutasteride; Efalizumab, eglumetad hydrate, emoxipin hydrochloride, eplerenone, erlotinib hydrochloride, escitalopram oxalate, etonogestrel/ethinylestradiol; Garenoxacin mesilate, gamma-hydroxybutyrate sodium, gefitinib; H5N1 pandemic influenza vaccine, human growth hormone-(177-191), human insulin; Indacaterol, INKP-100, INKP-102, insulin glargine, i.v. gamma-globulin; KLH; Lapatinib, L-arginine hydrochloride, lasofoxifene tartrate, levocetirizine, licochalcone A, LMI vaccine, lomefloxacin, lubiprostone, lumiracoxib; Miglustat, mycograb; Natalizumab, NCX-4016, nortopixantrone hydrochloride; Olmesartan medoxomil, omalizumab, oral insulin, OrM3; Parathyroid hormone (human recombinant), parecoxib sodium, PCK-3145, PEG-filgrastim, peginterferon alfa-2a, pemetrexed disodium, pexelizumab, photochlor, pimecrolimus, pneumococcal 7-valent conjugate vaccine, polyphenon E; R-126638, R-411, resveratrol, roflumilast, RS-86, ruboxistaurin mesilate hydrate, rupatadine fumarate; Sipuleucel-T, somatropin, St. John's Wort extract; Tadalafil, Taxus, telbivudine, telithromycin, temsirolimus, teriparatide, teverelix, tigecycline, tiotropium bromide, tolterodine, tolvaptan, treprostinil sodium, typhoid vaccine; Vardenafil hydrochloride hydrate, vildagliptin, voriconazole; Ximelagatran; Zanolimumab, zileuton."
3. Carcinoma (Carcinomatosis)
4. Neoplasm Metastasis (Metastasis)
5. Renal Cell Carcinoma (Grawitz Tumor)

Related Drugs and Biologics

1. bevacizumab
2. Biological Markers (Surrogate Marker)
3. 15-deoxy-delta(12,14)-prostaglandin J2
4. matrigel
5. troglitazone (Rezulin)
6. Cisplatin (Platino)
7. Thrombospondins
8. Paclitaxel (Taxol)
9. Peptides
10. Diethylstilbestrol (Stilbestrol)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Drug Therapy (Chemotherapy)
3. Stents
4. Radiotherapy
5. Euthanasia (Mercy Killing)