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labedipinedilol A

Receptors, Adrenergic, alpha antagonist; structure in first source

Also Known As:

labedipinedilol-A

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chen, Ing-Jun: 6 articles (02/2013 - 11/2004)
2.	Liou, Shu-Fen: 6 articles (02/2013 - 11/2004)
3.	Yeh, Jwu-Lai: 6 articles (02/2013 - 11/2004)
4.	Liang, Jyh-Chong: 3 articles (02/2013 - 11/2004)
5.	Hsu, Jong-Hau: 2 articles (02/2013 - 08/2011)
6.	Wu, Jiunn-Ren: 2 articles (08/2011 - 03/2005)
7.	Chiu, Chaw-Chi: 2 articles (08/2006 - 11/2004)
8.	Chen, Huai-Min: 1 article (08/2011)
9.	Dai, Zen-Kong: 1 article (08/2011)
10.	Lin, Hung-Hong: 1 article (02/2009)

Related Diseases

1.	Atherosclerosis 11/01/2004 - "These results indicate that labedipinedilol-A may inhibit cell proliferation by attenuating activation of the ERK 1/2 pathway, which is regulated by PKC and Ca, suggesting that it may have great potential in the prevention of progressive atherosclerosis." 08/01/2011 - "Thus, labedipinedilol-A may have a valuable role in the preventing atherosclerosis associated with hyperlipidemia."
2.	Myocardial Ischemia (Ischemic Heart Diseases) 08/22/2006 - "The effects of labedipinedilol-A, a novel dihydropyridine-type calcium channel blocker with alpha-/beta-adrenoceptor blocking activities, on myocardial infarct size, apoptosis and necrosis in the rat after myocardial ischemia/reperfusion (45 min/120 min) were investigated. "
3.	Reperfusion Injury 08/22/2006 - "Protective effect of labedipinedilol-A, a novel dihydropyridine-type calcium channel blocker, on myocardial apoptosis in ischemia-reperfusion injury."
4.	Vascular Diseases (Vascular Disease) 02/01/2013 - "These findings implicate a valuable role of new generation dihydropyridine CCBs lercanidipine and labedipinedilol-A for the treatment of inflammatory vascular diseases."
5.	Prostatic Neoplasms (Prostate Cancer) 02/04/2009 - "In this research, we conducted an in vitro analysis to evaluate the prostate cancer cells response to labedipinedilol-A in order to determine the effect of this selective alpha(1)-adrenoceptor antagonist to suppress prostate cancer cell growth by affecting cell proliferation and apoptosis. " 02/04/2009 - "Inhibition of human prostate cancer cells proliferation by a selective alpha1-adrenoceptor antagonist labedipinedilol-A involves cell cycle arrest and apoptosis." 02/04/2009 - "Here, we report that treatment of androgen-sensitive (LNCaP) and androgen-insensitive (PC-3) prostate cancer cells with labedipinedilol-A inhibited cell proliferation in concentration-dependent and time-dependent manners. "

Related Drugs and Biologics

1.	1,4-dihydropyridine (dihydropyridine)
2.	HMGB1 Protein (HMG1)
3.	Adrenergic Receptors (Adrenergic Receptor)
4.	Lipopolysaccharides
5.	Interferons
6.	Calcium Channel Blockers (Blockers, Calcium Channel)
7.	Calcium
8.	Androgens
9.	lercanidipine