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octa-arginine peptide

Also Known As:

D-R8 octamer; D-arginine octamer; R8 peptide; octa-Arg peptide

Networked: 5 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - octa-arginine peptide: 5

Experts

1.	He, Qin: 2 articles (06/2015 - 05/2015)
2.	Wang, Yang: 2 articles (06/2015 - 05/2015)
3.	Zhang, Li: 2 articles (06/2015 - 05/2015)
4.	Afouna, Mohsen I: 1 article (01/2022)
5.	Akl, Mohamed A: 1 article (01/2022)
6.	El-Gamal, Farid R: 1 article (01/2022)
7.	Kawakami, Shigeru: 1 article (01/2022)
8.	Mowafy, Hammam A: 1 article (01/2022)
9.	Mukai, Hidefumi: 1 article (01/2022)
10.	Gao, Hui-le: 1 article (06/2015)

Related Diseases

1.	Glioma (Gliomas) 01/01/2022 - "The objective of the current study is to develop novel octaarginine (R8) peptide-HFQ lipid grafted PEGylated liposomes for glioma cells targeting. "
2.	Breast Neoplasms (Breast Cancer) 06/01/2015 - "The purpose of the study is to construct R8 peptide (RRRRRRRR) and pH sensitive polyethylene glycols (PEG) co-modified liposomes (Cl-Lip) and utilize them in breast cancer treatment. "
3.	Acute Liver Failure (Fulminant Hepatic Failure) 03/01/2012 - "In this paper, we investigated whether quantum dots (QDs) labeling using octa-arginine peptide (R8) for ASCs could be applied for in vivo fluorescence imaging in mice with acute liver failure, and analyzed the behavior and organ-specific accumulation of ASCs that were transplanted alone or in combination with heparin using an IVIS(®) Spectrum analysis. "
4.	Prostatic Neoplasms (Prostate Cancer) 05/01/2006 - "Here, molecules based on the d-arginine octamer (r8) protein-transduction domain (PTD, also referred to as molecular transporters) have been adapted for selective uptake into cells only after proteolytic cleavage of a PTD-attenuating sequence by the prostate-specific antigen (PSA), an extracellular protease associated with the surface and microenvironment of certain prostate cancer cells. "
5.	Neoplasms (Cancer) 05/13/2015 - "When the Cl-Lip reached to the tumor site by the enhanced permeability and retention (EPR) effect, PEG(5K)-Hydrazone-PE was hydrolyzed from the Cl-Lip under the low extra-cellular pH conditions of tumors, then the R8 peptide was exposed, and finally liposomes could be internalized into tumor cells by the mediation of R8 peptide. "

Related Drugs and Biologics

1.	Liposomes (Liposome)
2.	Polyethylene Glycols (Polyethylene Glycol)
3.	Lipids
4.	octaarginine
5.	Prostate-Specific Antigen (Semenogelase)
6.	Proteins (Proteins, Gene)
7.	Peptide Hydrolases (Proteases)
8.	Heparin (Liquaemin)

Related Therapies and Procedures

1.	Quantum Dots (Quantum Dot)