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6- acetyl- 8- cyclopentyl- 5- methyl- 2- (5- piperazin- 1- ylpyridin- 2- ylamino)- 8H- pyrido(2,3- d)pyrimidin- 7- one

specific inhibitor of cyclin-dependent kinases 4 & 6; structure in first source
Also Known As:
PD 0332991; PD-0332991; PD0332991
Networked: 54 relevant articles (4 outcomes, 13 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Chen-Kiang, Selina: 5 articles (05/2015 - 08/2006)
2. Di Liberto, Maurizio: 5 articles (05/2015 - 08/2006)
3. Huang, Xiangao: 4 articles (05/2015 - 07/2008)
4. Toogood, Peter L: 4 articles (07/2008 - 11/2004)
5. Ely, Scott: 3 articles (09/2014 - 08/2006)
6. Martin, Peter: 3 articles (09/2014 - 05/2012)
7. Leonard, John P: 3 articles (09/2014 - 05/2012)
8. Randolph, Sophia: 3 articles (07/2014 - 03/2011)
9. Ginther, Charles: 3 articles (08/2013 - 01/2009)
10. Slamon, Dennis J: 3 articles (08/2013 - 01/2009)

Related Diseases

1. Neoplasms (Cancer)
2. Glioblastoma (Glioblastoma Multiforme)
3. Reperfusion Injury
4. Sarcoma (Soft Tissue Sarcoma)
5. Breast Neoplasms (Breast Cancer)

Related Drugs and Biologics

1. temozolomide (Temodar)
2. Cyclin-Dependent Kinase 4
3. Cyclin D1
4. Retinoblastoma Protein
5. flavopiridol
6. Small Interfering RNA (siRNA)
7. Glucose (Dextrose)
8. Dihydrotachysterol (AT 10)
9. Phosphotransferases (Kinase)
10. Cyclins

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Drug Therapy (Chemotherapy)
3. Oral Administration