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4- amino- 5- fluoro- 3- (5- (4- methylpiperazin- 1- yl)- 1H- benzimidazol- 2- yl)quinolin- 2(1H)- one

multitargeted tyrosine kinase inhibitor for the potential treatment of t(4;14) multiple myeloma
Also Known As:
CHIR 258; CHIR-258; CHIR258; TKI 258; TKI-258; TKI258
Networked: 30 relevant articles (4 outcomes, 12 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Heise, Carla: 4 articles (04/2008 - 04/2005)
2. Shi, Michael: 3 articles (06/2014 - 03/2013)
3. Konecny, Gottfried E: 2 articles (06/2015 - 05/2013)
4. Zhou, Yongan: 2 articles (09/2014 - 09/2014)
5. Li, Xinhua: 2 articles (09/2014 - 09/2014)
6. Eucker, Jan: 2 articles (09/2014 - 09/2014)
7. Habbel, Piet: 2 articles (09/2014 - 09/2014)
8. Zang, Chuanbing: 2 articles (09/2014 - 09/2014)
9. Liu, Hongyu: 2 articles (09/2014 - 09/2014)
10. Scholz, Christian: 2 articles (09/2014 - 09/2014)

Related Diseases

1. Neoplasms (Cancer)
2. Leukemia
3. Pancreatic Neoplasms (Pancreatic Cancer)
4. Endometrial Neoplasms (Endometrial Cancer)
5. Renal Cell Carcinoma (Grawitz Tumor)

Related Drugs and Biologics

1. Protein-Tyrosine Kinases (Tyrosine Kinase)
2. everolimus
3. Phosphotransferases (Kinase)
4. tyrosine receptor (receptor, tyrosine)
5. Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)
6. Vascular Endothelial Growth Factor Receptors (VEGF Receptors)
7. Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)
8. Biological Markers (Surrogate Marker)
9. 4- amino- 5- fluoro- 3- (5- (4- methylpiperazin- 1- yl)- 1H- benzimidazol- 2- yl)quinolin- 2(1H)- one
10. Histone Deacetylase Inhibitors

Related Therapies and Procedures

1. Oral Administration
2. Heterologous Transplantation (Xenotransplantation)