|1.||Yue, Ling: 1 article (10/2015)|
|2.||Zhao, Wenhao: 1 article (10/2015)|
|3.||Xu, Chan: 1 article (10/2015)|
|4.||Yang, Jing: 1 article (10/2015)|
|5.||Yang, Xinzhou: 1 article (10/2015)|
|6.||Shu, Guangwen: 1 article (10/2015)|
|7.||Wang, Shaobing: 1 article (10/2015)|
|8.||Zhang, Xiyu: 1 article (01/2015)|
|9.||Li, Boxuan: 1 article (01/2015)|
|10.||Gong, Yaoqin: 1 article (01/2015)|
|1.||Breast Neoplasms (Breast Cancer)
01/01/2015 - "Our findings thus revealed a novel antitumor effect of isoliensinine on breast cancer cells and may have therapeutic implications. "
01/01/2015 - "Further studies showed that isoliensinine could significantly increase the production of reactive oxygen species (ROS) in triple-negative breast cancer cells, but not in MCF-10A cells. "
01/01/2015 - "Here, we explored the effects of these alkaloids on triple-negative breast cancer cells and found that among the three alkaloids isoliensinine possesses the most potent cytotoxic effect, primarily by inducing apoptosis. "
01/01/2015 - "Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation."
|2.||Pulmonary Fibrosis (Hamman Rich Syndrome)
03/01/2005 - "Inhibitory effects of isoliensinine on bleomycin-induced pulmonary fibrosis in mice."
03/01/2005 - "The effects of isoliensinine (IL), a bisbenzylisoquinoline alkaloid extracted from the Chinese traditional medicine seed embryo of Nelumbo nucifera Gaertn., on bleomycin (BLM)-induced pulmonary fibrosis in mice were investigated. "
01/01/2015 - "The isoliensinine-induced apoptosis could be attenuated by radical oxygen scavenger N-acetyl cysteine, suggesting that the cytotoxic effect of isoliensinine on cancer cells is at least partially achieved by inducing oxidative stress. "
01/01/2015 - "Isoliensinine, liensinine and neferine are major bisbenzylisoquinoline alkaloids in the seed embryo of lotus (Nelumbo nucifera), and exhibit potential anti-cancer activity. "
|4.||Hepatocellular Carcinoma (Hepatoma)
|1.||Reactive Oxygen Species (Oxygen Radicals)
|3.||p38 Mitogen-Activated Protein Kinases
|1.||Chinese Traditional Medicine (Traditional Chinese Medicine)