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psychollatine

from Psychotria umbellata; structure in first source

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - psychollatine: 2
Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Indole Alkaloids: 200
    - psychollatine: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Indole Alkaloids: 200
        psychollatine: 2
    - Indolizines: 3
      - Indolizidines: 2
        Indole Alkaloids: 200
        psychollatine: 2

Experts

1.	Both, Fernanda L: 2 articles (03/2006 - 03/2005)
2.	Elisabetsky, Elaine: 2 articles (03/2006 - 03/2005)
3.	Henriques, Amélia T: 2 articles (03/2006 - 03/2005)
4.	Kerber, Vitor A: 2 articles (03/2006 - 03/2005)
5.	Meneghini, Lisiane: 2 articles (03/2006 - 03/2005)

Related Diseases

1.	Seizures (Absence Seizure) 03/01/2006 - "Psychollatine (1) (100 mg/kg) and MK-801 (0.3 mg/kg) prevented NMDA-induced seizures (P < 0.01), while 1 (100 mg/kg) attenuated the MK-801-induced hyperlocomotion (P < 0.05). " 03/01/2006 - "This study aimed to investigate the role of NMDA glutamate and dopamine receptors in mediating the properties of 1. Psychollatine (1) was assessed for NMDA-induced seizures, MK-801-induced hyperlocomotion, amphetamine-induced lethality, and apomorphine-induced climbing behavior in mice. "
2.	Tremor (Tremors) 03/01/2005 - "Psychollatine suppressed oxotremorine-induced tremors in all doses. " 03/01/2005 - "Behavioral effects of psychollatine, a new glycoside indole monoterpene alkaloid isolated from Psychotria umbellata, was investigated in models of anxiety, depression, memory, tremor, and sedation related to 5-HT and/or GABA neurotransmission. "

Related Drugs and Biologics

1.	Glutamic Acid (Glutamate)
2.	N-Methylaspartate (NMDA)
3.	Dopamine Receptors (Dopamine Receptor)
4.	Apomorphine
5.	Amphetamine (Amfetamine)
6.	Monoterpenes (Monoterpenoids)
7.	Dizocilpine Maleate (Dizocilpine)
8.	Serotonin (5 Hydroxytryptamine)
9.	Oxotremorine
10.	Glycosides