Ralfinamide

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2 relevant articles (0 outcomes, 2 trials/studies) found for this Bio-Agent

Description: Sodium Channel Blocker; structure in first source

Also Known As:

2-(((4-((2-fluorophenyl)methoxy)phenyl)methyl)amino)propanamide

Bio-Agent Context: Research Results

Organic Chemicals: 40

Hydrocarbons: 382

Halogenated Hydrocarbons: 28

Fluorinated Hydrocarbons: 2

Fluorobenzenes

Ralfinamide: 2

Related Diseases

Pain (Aches)

10/15/2008 - "Ralfinamide is analgesic when applied as a single dose in rodent models of stimulus-evoked chronic pain"
10/15/2008 - "Ralfinamide administered orally before hindpaw neurectomy or postoperatively provided long-lasting suppression of spontaneous neuropathic pain-related behavior in the rat."
11/01/2007 - "The action of ralfinamide to selectively inhibit tonic firing in nociceptive neurons very likely contributes to the effectiveness of the drug in reducing inflammatory and neuropathic pain as well as bladder overactivity."
10/15/2008 - "In this study ralfinamide was administered to rats at doses producing plasma levels similar to those causing analgesia in pain patients"
11/01/2007 - "Recent studies revealed that ralfinamide, a Na(+) channel blocker, suppressed tetrodotoxin-resistant Na(+) currents in dorsal root ganglion (DRG) neurons and reduced pain reactions in animal models of inflammatory and neuropathic pain"
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1 Diseases and 2 more articles analyzed in the Research Interface, order at left...

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3 Drugs and Important Bio-Agents and 2 more articles analyzed in the Research Interface, order at left...

Related Therapies and Procedures

1.	Analgesia
1 Therapies and Procedures and 1 more articles analyzed in the Research Interface, order at left...

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