Chunghyuldan

has been used as an antihyperlipidemic and antiischemic agent in Korea; CHD showed antioxidant activities in vitro, and inhibited nitric oxide (NO) and prostaglandin E2 (PGE2) productions in lipopolysaccharide (LPS)-induced RAW264.7 cells

Networked: 9 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Cho, Ki-Ho: 4 articles (12/2013 - 12/2005)
2.	Kim, Hyo Geun: 3 articles (06/2014 - 12/2010)
3.	Oh, Myung Sook: 3 articles (06/2014 - 12/2010)
4.	Jung, Woo-Sang: 3 articles (12/2013 - 12/2005)
5.	Lee, Eunjoo H: 3 articles (09/2011 - 06/2009)
6.	Kang, Chulhun: 2 articles (12/2013 - 06/2009)
7.	Ko, Chang-Nam: 2 articles (12/2013 - 12/2005)
8.	Moon, Sang-Kwan: 2 articles (12/2013 - 12/2005)
9.	Park, Seong-Uk: 2 articles (12/2013 - 12/2005)
10.	Kim, Sun Yeou: 2 articles (09/2011 - 12/2010)

Related Diseases

1.	Stroke (Strokes) 06/01/2009 - "Chunghyuldan, a combinatorial drug consisting of Scutellariae Radix, Coptidis Rhizoma, Phellodendri Cortex, Gardeniae Fructus, and Rhei Rhizoma, has an inhibitory effect on stroke recurrence in patients with small-vessel disease. " 12/01/2005 - "Chunghyuldan (CHD), a combinatorial drug that has antihyperlipidemic and anti-inflammatory activities, has been shown to improve arterial stiffness and inhibit stroke recurrence in clinical study. " 06/01/2014 - "Chunghyuldan (CHD; Qingxue-dan in Chinese and Daio-Orengedokuto in Japanese) possesses wide-ranging biological effects, including anti-hyperlipidemic, anti-stroke, anti-inflammatory, and antioxidant activities that could affect neurological functions. " 02/13/2023 - "Neuroprotective Effects of Geopung-Chunghyuldan Based on Its Salvianolic Acid B Content Using an In Vivo Stroke Model."
2.	Parkinson Disease (Parkinson's Disease) 12/01/2010 - "Protective effects of Chunghyuldan against ROS-mediated neuronal cell death in models of Parkinson's disease."
3.	Memory Disorders (Memory Loss) 09/01/2011 - "The present study utilized a mouse model of AD induced by intrahippocampal injection of AβO (10 μM) to investigate the effects of Gami-Chunghyuldan (GCD), a standardized multi-herbal medicinal formula, on the presentation of memory deficits and neurohistological pathogenesis. "
4.	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 04/15/2023 - "A Comparative Study on the Neuroprotective Effect of Geopung-Chunghyuldan on In Vitro Oxygen-Glucose Deprivation and In Vivo Permanent Middle Cerebral Artery Occlusion Models."
5.	Neuroblastoma 12/01/2013 - "Neuroprotective effect of Chunghyuldan (Qing Xue Dan) on hypoxia-reoxygenation induced damage of neuroblastoma 2a cell lines."

Related Drugs and Biologics

1.	Hypolipidemic Agents (Antihyperlipidemics)
2.	Neuroprotective Agents
3.	Amyloid beta-Peptides
4.	Oxygen (Dioxygen)
5.	Oxazolone
6.	Glucose (Dextrose)
7.	Antioxidants
8.	salvianolic acid B