rubratin

a cell wall preparation of Nocaradia rubra that has immunostimulant activity; used during treatment of bladder cancer

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

1.	Urinary Bladder Neoplasms (Bladder Cancer) 09/01/2000 - "Twelve patients with superficial bladder cancer were treated with intravesical instillations of Rubratin (ASTA Pharma AG, Frankfurt, Germany), a cell-wall preparation of Nocardia rubra. " 09/01/2000 - "Immunostimulation in the urinary bladder by local application of Nocardia rubra cell-wall skeletons (Rubratin) and bacillus Calmette-Guérin as therapy for superficial bladder cancer: a comparative study." 01/01/1997 - "Immunostimulation in the urinary bladder by local application of Nocardia rubra cell wall skeleton preparation (Rubratin) for superficial bladder cancer immunotherapy--a phase I/II study."
2.	Neoplasms (Cancer) 01/01/1997 - "Urinary cytokine induction by Rubratin was comparable with cytokine induction observed in nonresponding bacillus Calmette-Guérin (BCG) patients (recurrent tumor within 6 months), but less compared with responding BCG patients (no recurrent tumor within 6 months). "
3.	Transitional Cell Carcinoma 01/01/1997 - "Twelve patients with superficial papillary transitional cell carcinoma of the bladder (pTa, pT1) were treated with six consecutive weekly intravesical instillations of Rubratin (in a dose of 1.5, 3.0, or 4.5 mg), a cell wall skeleton preparation of Nocardia rubra (NCW). "

1.	Immunotherapy
2.	Intravesical Administration
3.	Therapeutics