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mouse TIRAP protein

an adapter protein involved in TLR-4 signal transduction in the inate immune response; acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, resulting in cytokine secretion and the inflammatory response; RefSeq NM_054096
Also Known As:
TIRAP protein, mouse; MyD88-adapter-like protein, mouse; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein, mouse; wyatt protein, mouse
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Bio-Agent Context: Research Results