17alpha- acetoxy- 3beta- butanoyloxy- 6- methyl- pregna- 4,6- dien- 20- one

Also Known As:

butagest; buterol

Networked: 4 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Pregnanes: 9
      - Pregnenes: 1
        Pregnenediones
        Progesterone: 12723
        Hydroxyprogesterones
        17-alpha-Hydroxyprogesterone: 804
        17alpha-acetoxy-3beta-butanoyloxy-6-methyl-pregna-4,6-dien-20-one: 4
Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Gonadal Hormones: 716
    - Gonadal Steroid Hormones: 7657
      - Progesterone Congeners: 320
        Progesterone: 12723
        Hydroxyprogesterones
        17-alpha-Hydroxyprogesterone: 804
        17alpha-acetoxy-3beta-butanoyloxy-6-methyl-pregna-4,6-dien-20-one: 4

Experts

1.	Fedotcheva, T A: 2 articles (07/2004 - 11/2003)
2.	Grinenko, G S: 2 articles (07/2004 - 11/2003)
3.	Rzheznikov, V M: 2 articles (07/2004 - 11/2003)
4.	Sergeev, P V: 2 articles (07/2004 - 11/2003)
5.	Fedotcheva, Nadezhda I: 1 article (10/2009)
6.	Fedotcheva, Tatiana A: 1 article (10/2009)
7.	Rzheznikov, Vladimir M: 1 article (10/2009)
8.	Shimanovskii, Nikolai L: 1 article (10/2009)
9.	Teplova, Vera V: 1 article (10/2009)
10.	Fedosov, A V: 1 article (07/2004)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 07/01/2004 - "Thus, the new gestagen 17alpha-acetoxy-3beta-butanoyloxy-6-methyl-pregna-4,6-dien-20-one is capable of suppressing the viability of human breast carcinoma and human cervical carcinoma, being comparable or even more effective than the reference drugs." 11/01/2003 - "The combined cytostatic effect of doxorubicin and gestagens progesterone, medroxyprogesterone acetate, mecigestone, and butagest on doxorubicin-resistant and doxorubicin-sensitive human breast cancer MCF-7 cells was studied by the MTT assay. "
2.	Carcinoma (Carcinomatosis) 07/01/2004 - "Thus, the new gestagen 17alpha-acetoxy-3beta-butanoyloxy-6-methyl-pregna-4,6-dien-20-one is capable of suppressing the viability of human breast carcinoma and human cervical carcinoma, being comparable or even more effective than the reference drugs." 07/01/2004 - "Antitumor activity of a new highly active promising gestagen 17alpha-acetoxy-3beta-butanoyloxy-6-methyl-pregna-4,6-dien-20-one (butagest) was studied in mice with model cervical carcinoma (RShM-5). "
3.	Neoplasms (Cancer) 10/15/2009 - "These data indicate that buterol interacts with thiol groups, which explains its inhibitory effect not only on the mitochondrial pore but also on the transport system of xenobiotics in tumor cells in which buterol reduces the multidrug resistance."
4.	Premature Obstetric Labor (Premature Labor) 01/01/2002 - "The ability of a series of new 17 alpha-Hydroxyprogesteron derivatives (acetomepregnol, AMOL phenyl propyoate, butagest) in preventing the prostaglandin-induced preterm labor was experimentally studied in mice. "

Related Drugs and Biologics

1.	Progestins (Progestagens)
2.	17alpha- acetoxy- 3beta- butanoyloxy- 6- methyl- pregna- 4,6- dien- 20- one
3.	Cytostatic Agents
4.	Medroxyprogesterone Acetate (Depo-Provera)
5.	Xenobiotics
6.	Sulfhydryl Compounds (Thiols)
7.	Prostaglandins
8.	Progesterone
9.	Doxorubicin (Adriamycin)