Member 1 Group D Nuclear Receptor Subfamily 1

A DNA-binding orphan nuclear receptor that negatively regulates expression of ARNTL TRANSCRIPTION FACTORS and plays a role as a regulatory component of the circadian clock system. The Nr1d1 nuclear receptor expression is cyclically-regulated by a feedback loop involving its positive regulation by CLOCK PROTEIN; BMAL1 PROTEIN heterodimers and its negative regulation by CRYPTOCHROME and PERIOD PROTEINS.

Also Known As:

Nuclear Receptor Subfamily 1, Group D, Member 1; Nuclear Receptor NR1D1; V-erbA-Related Protein EAR-1; NR1D1, Nuclear Receptor; Nuclear Receptors, Rev-erb-alpha; Receptor NR1D1, Nuclear; Rev erb alpha Nuclear Receptors; V erbA Related Protein EAR 1; Rev-erb-alpha Nuclear Receptors

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Cytoplasmic and Nuclear Receptors: 3987
    - Orphan Nuclear Receptors: 423
      - Member 1 Group D Nuclear Receptor Subfamily 1: 28
  - DNA-Binding Proteins: 2009
    - Orphan Nuclear Receptors: 423
      - Member 1 Group D Nuclear Receptor Subfamily 1: 28
  - Intracellular Signaling Peptides and Proteins: 32
    - Circadian Rhythm Signaling Peptides and Proteins
      - Member 1 Group D Nuclear Receptor Subfamily 1: 28

mouse Nr1d1 protein

Bio-Agent Context: Research Results