B7-2 Antigen

A costimulatory ligand glycoprotein that contains a C2 and V-type IMMUNOGLOBULIN DOMAIN. It is expressed by ANTIGEN-PRESENTING CELLS and binds to CD28 ANTIGEN with high specificity and to CTLA-4 ANTIGEN with low specificity. The interaction of CD86 with CD28 ANTIGEN provides a stimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.

Also Known As:

Antigen, B7-2; B70 Costimulatory Molecule; CD86 Antigen; Early T Cell Costimulatory Molecule 1; Antigen, B7 2; Antigen, CD86; B7 2 Antigen; Costimulatory Molecule, B7-2; Costimulatory Molecule, B70; Antigens, CD86; B7-2 Costimulatory Molecule; CD86 Antigens

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - B7 Antigens: 157
      - B7-2 Antigen: 25
  - Membrane Proteins: 10078
    - B7 Antigens: 157
      - B7-2 Antigen: 25
  - Immune Checkpoint Proteins: 1217
    - B7-2 Antigen: 25
Biological Factors: 2472
- Antigens: 143924
  - Surface Antigens: 5813
    - B7 Antigens: 157
      - B7-2 Antigen: 25
- Intercellular Signaling Peptides and Proteins: 29768
  - B7 Antigens: 157
    - B7-2 Antigen: 25

human CD86 protein

Bio-Agent Context: Research Results